Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Brazil.
Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Brazil.
Exp Gerontol. 2020 Sep;138:110973. doi: 10.1016/j.exger.2020.110973. Epub 2020 May 23.
To compare the effects of high-load (≥ 70 of 1RM) and low-load (< 70 of 1RM) resistance training (RT) on femoral neck and lumbar spine bone mineral density (BMD) in middle-aged and older people.
Systematic review with meta-analysis.
English language searches of the electronic databases PubMed/Medline, Scopus and Web of Science.
(i) older or middle-aged (≥ 45 years old) participants of both sexes with or without comorbidities, (ii) studies that compared high-load (≥70% 1 RM) versus low-load (<70% 1RM) RT, (iii) studies that examined femoral neck or lumbar spine BMD.
From 1052 studies found, six were included in qualitative and quantitative analysis. The meta-analysis revealed no difference between groups for femoral neck (weighted mean difference [MD] and 95% confidence interval (CI) = 0.00 g/cm [95% CI, -0.01 to 0.01]; P = 0.63) and lumbar spine (MD = 0.01 g/cm [95% CI, -0.00 to 0.02]; P = 0.12) BDM. There was a substantial heterogeneity for femoral neck (I = 47%; P = 0.07) and lumbar spine (I = 59%; P = 0.02). Subgroup analysis revealed a significant effect of high-load RT on femoral neck BMD when participants presented normal BMD values (MD = 0.01 g/cm [95% CI, -0.00 to 0.02]; P = 0.04) and on interventions lasting up to 6 months (MD = 0.01 g/cm [95% CI, -0.00 to 0.02]; P = 0.03).
Both high- and low-load RT have similar effects on femoral neck and lumbar spine BMD in aging people.
比较高负荷（≥1RM 的 70%）和低负荷（<1RM 的 70%）抗阻训练（RT）对中年和老年人股骨颈和腰椎骨密度（BMD）的影响。
系统评价和荟萃分析。
对电子数据库 PubMed/Medline、Scopus 和 Web of Science 进行英文检索。
（i）年龄较大或中年（≥45 岁）的男女受试者，无论是否存在合并症，（ii）比较高负荷（≥70%1RM）与低负荷（<70%1RM）RT 的研究，（iii）检查股骨颈或腰椎 BMD 的研究。
从 1052 项研究中，有 6 项研究纳入了定性和定量分析。荟萃分析显示，两组之间股骨颈（加权均数差 [MD] 和 95%置信区间 [CI]：0.00 g/cm [95%CI，-0.01 至 0.01]；P=0.63）和腰椎 BMD （MD=0.01 g/cm [95%CI，-0.00 至 0.02]；P=0.12）均无差异。股骨颈（I=47%；P=0.07）和腰椎（I=59%；P=0.02）的异质性较大。亚组分析显示，当参与者的 BMD 值正常时，高负荷 RT 对股骨颈 BMD 有显著影响（MD=0.01 g/cm [95%CI，-0.00 至 0.02]；P=0.04），并且在持续时间长达 6 个月的干预中也有显著影响（MD=0.01 g/cm [95%CI，-0.00 至 0.02]；P=0.03）。
高负荷和低负荷 RT 对衰老人群的股骨颈和腰椎 BMD 有相似的影响。
