Tomonaga K, Kurono Y, Mogi G
Department of Otolaryngology, Medical College of Oita, Japan.
Acta Otolaryngol Suppl. 1988;458:41-7. doi: 10.3109/00016488809125100.
In order to clarify the role of Type I immunologic reactions in the etiology of otitis media with effusion (OME), kindergarten and elementary school children were given routine nasal allergy (NA) tests and otologic tests. Several children among them were evaluated for eustachian tube (ET) function before and after the intranasal histamine challenge, using the inflation-deflation test, and the nine-step inflation and deflation tympanometric test. The results clarified that NA-patients showed a high ratio (21%) of complication with OME, and that OME-patients showed a high ratio (50%) of complication with NA. It was also found that the incidence of tubal dysfunction was higher in OME-patients with NA than in OME-patients without NA. The man period of time between the removal and replacement of a tympanostomy tube was 11 months in OME-patients with NA who underwent hyposensitization; whereas the mean period of time was 2 months in OME-patients with NA who underwent no treatment for NA. The findings of the present study suggest that NA affects tubal function (even if the effect is temporary), and that NA may be a risk factor in OME-prone children.
为了阐明I型免疫反应在分泌性中耳炎（OME）病因学中的作用，对幼儿园和小学儿童进行了常规鼻过敏（NA）测试和耳科检查。其中几名儿童在鼻内组胺激发试验前后，使用充气-放气试验以及九步充气和放气鼓室导抗测试评估了咽鼓管（ET）功能。结果表明，NA患者中OME并发症的发生率较高（21%），而OME患者中NA并发症的发生率较高（50%）。还发现，伴有NA的OME患者的咽鼓管功能障碍发生率高于不伴有NA的OME患者。接受减敏治疗的伴有NA的OME患者，鼓膜造孔管取出和更换之间的平均时间为11个月；而未接受NA治疗的伴有NA的OME患者，平均时间为2个月。本研究结果表明，NA会影响咽鼓管功能（即使这种影响是暂时的），并且NA可能是易患OME儿童的一个危险因素。
