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2
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Mol Nutr Food Res. 2018 Jul;62(14):e1701073. doi: 10.1002/mnfr.201701073. Epub 2018 Jun 19.
3
Berry Phenolic Antioxidants - Implications for Human Health?浆果酚类抗氧化剂——对人类健康有何影响?
Front Pharmacol. 2018 Mar 26;9:78. doi: 10.3389/fphar.2018.00078. eCollection 2018.
4
Coumarin Compounds in Medicinal Chemistry: Some Important Examples from the Last Years.香豆素类化合物在药物化学中的应用:近年来的一些重要实例。
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Anti-inflammatory effect of corymbocoumarin from Seseli gummiferum subsp. corymbosum through suppression of NF-κB signaling pathway and induction of HO-1 expression in LPS-stimulated RAW 264.7 cells.伞形科植物胶管邪蒿亚种伞状邪蒿中伞形香豆素通过抑制NF-κB信号通路和诱导LPS刺激的RAW 264.7细胞中HO-1表达发挥抗炎作用。
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A new subspecies of Seseli gummiferum (Apiaceae) from Ilgaz Mountain National Park, northern Turkey.来自土耳其北部伊尔加兹山国家公园的胶管邪蒿(伞形科)一新亚种。
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Secondary metabolites of Seseli rigidum: Chemical composition plus antioxidant, antimicrobial and cholinesterase inhibition activity.硬叶邪蒿的次生代谢产物:化学成分及其抗氧化、抗菌和胆碱酯酶抑制活性
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9
New insights into the chemistry and antioxidant activity of coumarins.香豆素的化学性质与抗氧化活性新见解
Curr Top Med Chem. 2014;14(22):2600-23. doi: 10.2174/1568026614666141203144551.
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Application of stepwise gradients in counter-current chromatography: a rapid and economical strategy for the one-step separation of eight coumarins from Seseli resinosum.逐步梯度在逆流色谱中的应用:从Seseli resinosum 中一步分离八种香豆素的快速经济策略。
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唇形科植物(伞形科)抗氧化能力的评估。

Evaluation of the Antioxidant Potency of L. Species (Apiaceae).

作者信息

Önder Alev, Çinar Ahsen Sevde, Yilmaz Sarialtin Sezen, Izgi Mehmet Necat, Çoban Tülay

机构信息

Ankara University Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey.

Lokman Hekim University Faculty of Pharmacy, Department of Pharmacognosy/Pharmaceutical Botany, Ankara, Turkey.

出版信息

Turk J Pharm Sci. 2020 Apr;17(2):197-202. doi: 10.4274/tjps.galenos.2019.80488. Epub 2020 Apr 24.

DOI:10.4274/tjps.galenos.2019.80488
PMID:32454780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7227918/
Abstract

OBJECTIVES

In the present study, the antioxidant potency of ethyl acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of L. species was investigated for the first time.

MATERIALS AND METHODS

species L. such as Woronow ex Schischk., Besser, Boiss. & Heldr., subsp. Pall. ex Sm., Parolly & Nordt, (L.) W.Koch, M.Bieb., (M.Bieb.) Koso-Pol., Freyn & Sint., and L. growing in Turkey were collected and evaluated for their antioxidant capacity by using 1.1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and lipid peroxidation (LPO) inhibition methods.

RESULTS

The highest activities as a scavenger of DPPH radicals were found in the AcOEt extracts of (M.Bieb.) Koso-Pol (IC=0.49 mg/mL), and (IC=0.75 mg/mL); α-tocopherol was used as a positive control. On the other hand, in the LPO assay, the highest activities were determined in AcOEt and MeOH extracts (at 5 mg/mL) of and (84-94%).

CONCLUSION

This report gives important information about the antioxidant capacity of L. species. This research on antioxidant capacity proves that the use of some species used in Eastern Anatolia (in salads) is correct. With this screening study performed in L. species growing in Turkey, in the future, it is planned to isolate antioxidant compounds from the most active strains of L.

摘要

目的

在本研究中,首次对L. 物种地上部分的乙酸乙酯(AcOEt)和甲醇(MeOH)提取物的抗氧化能力进行了研究。

材料与方法

收集了生长在土耳其的L. 物种,如Woronow ex Schischk.、Besser、Boiss. & Heldr.、subsp. Pall. ex Sm.、Parolly & Nordt、(L.) W.Koch、M.Bieb.、(M.Bieb.) Koso-Pol.、Freyn & Sint.以及L.,并通过1,1-二苯基-2-苦基肼(DPPH)自由基清除法和脂质过氧化(LPO)抑制法对其抗氧化能力进行评估。

结果

在(M.Bieb.) Koso-Pol的AcOEt提取物(IC = 0.49 mg/mL)和(IC = 0.75 mg/mL)中发现了最高的DPPH自由基清除活性;α-生育酚用作阳性对照。另一方面,在LPO测定中,在和的AcOEt和MeOH提取物(5 mg/mL)中测定到了最高活性(84 - 94%)。

结论

本报告提供了有关L. 物种抗氧化能力的重要信息。这项关于抗氧化能力的研究证明了东安纳托利亚(用于沙拉)的一些物种的使用是正确的。通过对生长在土耳其的L. 物种进行的这项筛选研究,未来计划从L. 最具活性的菌株中分离出抗氧化化合物。