Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Molecules. 2024 Jun 6;29(11):2694. doi: 10.3390/molecules29112694.
Gilli is a rare annual wild herb grown in Libya. It belongs to the Apiaceae family, which is one of the largest flowering plant families. Plants of this family are outstanding sources of various secondary metabolites with various biological activities. A UPLC-ESI-MS/MS analysis of different extracts of in vivo and in vitro tissues of together with the fruit extract of the cultivated plant in both ionization modes was carried out for the first time in the current study. Our results reveal the tentative identification of eighty-seven compounds in the tested extracts, including thirty-two phenolic acids and their derivatives; thirty-seven flavonoid glycosides and aglycones of apigenin, luteolin, diosmetin, myricetin and quercetin, containing glucose, rhamnose, pentose and/or glucuronic acid molecules; seven anthocyanins; six tannins; three acetylenic compounds; and three nitrogenous compounds. The tentative identification of the above compounds was based on the comparison of their retention times and ESI-MS/MS fragmentation patterns with those previously in the literature. For this Apiaceae plant, our results confirm the presence of a wide array of secondary metabolites with reported biological activities. This study is among the first ones to shed light on the phytoconstituents of this rare plant.
吉莉是一种生长在利比亚的罕见一年生野生草本植物。它属于伞形科，是最大的开花植物科之一。该科植物是具有各种生物活性的各种次生代谢物的杰出来源。本研究首次对体内和体外组织的不同提取物以及栽培植物果实提取物进行了 UPLC-ESI-MS/MS 分析，在这两种电离模式下进行了分析。我们的结果揭示了在测试提取物中鉴定出的八十七种化合物，包括三十二种酚酸及其衍生物；三十七个黄酮苷和芹菜素、木犀草素、香叶木素、杨梅素和槲皮素的苷元，含有葡萄糖、鼠李糖、戊糖和/或葡萄糖醛酸分子；七种花青素；六种鞣质；三种炔类化合物；和三种含氮化合物。上述化合物的初步鉴定是基于它们的保留时间和 ESI-MS/MS 碎片模式与文献中报道的化合物进行比较。对于这种伞形科植物，我们的结果证实了存在广泛的具有报道生物活性的次生代谢物。这项研究是首次阐明这种稀有植物的植物成分。
