Infection: Clinical, Endoscopic, and Histological Findings in Lebanese Pediatric Patients.

BACKGROUND

() is a common and universally distributed bacterial infection. However, in children, active gastritis and ulcer are rarely seen.

OBJECTIVES

The aims of this study were to establish the prevalence of infection and to compare the clinical, endoscopic, and histopathological findings between infected and noninfected pediatric patients at Makassed General Hospital.

METHODS

Patients aged between 1 month and 17 years who underwent upper gastrointestinal endoscopy from January 2011 to January 2017 were included. The diagnosis of was confirmed by a CLO test and/or its presence on biopsy specimens. Demographic data, clinical characteristics, endoscopic and histopathological findings, and gastritis score were recorded retrospectively.

RESULTS

During the study period, 651 children underwent upper gastrointestinal endoscopy. The main indication was abdominal pain (61%). The prevalence of infection was 16.5%. The infection was most commonly seen among children aged between 6 and 10 years (43%). A large number of family members were associated with increased risk of infection (4.8 ± 1.5 versus 5.2 ± 1.8; < 0.05). Epigastric pain was more associated with (61.3% versus 14.6% in noninfected patients; < 0.05). Nodular gastritis was commonly seen in infected patients (41.5% vs. 7.9%; < 0.05). Mild and moderate gastritis was seen more in infected versus noninfected patients (mild: 53.8% vs. 14%; moderate: 27.4% vs. 2.4%, respectively).

CONCLUSION

Although epigastric pain was associated with , other diagnoses should be considered since the infection are rarely symptomatic in children. Antral nodularity was associated with ; however, its absence does not preclude the diagnosis.