梅尼埃病患者的免疫状态。
Immune status in patients with Menière's disease.
作者信息
Evans K L, Baldwin D L, Bainbridge D, Morrison A W
机构信息
Department of Otolaryngology, London Hospital, Whitechapel, England.
出版信息
Arch Otorhinolaryngol. 1988;245(5):287-92. doi: 10.1007/BF00464632.
Sera of 164 patients with classical Meniere's disease were screened for autoantibodies, immune complexes and HLA status. Increased thyroid microsomal antibodies were significant in those patients in the 40- to 60-year age range. Raised IgM complexes and C1q component of complement were significant in all age groups. Low levels of IgA complexes were a consistent finding and were significantly lower in the HLA Cw7 group. Patients with migraine had no increased incidence of immune disturbances.
对164例典型梅尼埃病患者的血清进行自身抗体、免疫复合物和HLA状态筛查。甲状腺微粒体抗体升高在40至60岁年龄组的患者中具有显著意义。IgM复合物和补体C1q成分升高在所有年龄组中均具有显著意义。IgA复合物水平低是一个一致的发现，并且在HLA Cw7组中显著更低。偏头痛患者的免疫紊乱发生率没有增加。
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