University Center of Legal Medicine (CURML), Geneva University Hospital, Geneva, Switzerland.
Department of Pathology, Geneva University Hospital, Geneva, Switzerland.
Int J Legal Med. 2020 Jul;134(4):1271-1274. doi: 10.1007/s00414-020-02318-9. Epub 2020 May 26.
In the setting of the coronavirus disease 2019 (COVID-19) pandemic, only few data regarding lung pathology induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is available, especially without medical intervention interfering with the natural evolution of the disease. We present here the first case of forensic autopsy of a COVID-19 fatality occurring in a young woman, in the community. Diagnosis was made at necropsy and lung histology showed diffuse alveolar damage, edema, and interstitial pneumonia with a geographically heterogeneous pattern, mostly affecting the central part of the lungs. This death related to COVID-19 pathology highlights the heterogeneity and severity of central lung lesions after natural evolution of the disease.
在 2019 年冠状病毒病（COVID-19）大流行的背景下，关于严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）引起的肺部病理学，仅有少量数据，特别是在没有医疗干预干扰疾病自然演变的情况下。我们在此介绍首例社区内年轻女性 COVID-19 死亡的法医尸检案例。诊断是在尸检时做出的，肺组织学显示弥漫性肺泡损伤、水肿和间质性肺炎，呈地理上不均匀的模式，主要影响肺部的中央部分。这例与 COVID-19 病理学相关的死亡突出了疾病自然演变后中央肺部病变的异质性和严重性。
