Asherman 综合征：单一术者队列 423 例的回顾性分析。
Asherman syndrome: Audit of a single-operator cohort of 423 cases.
机构信息
Department of Women's and Children, University of New South Wales, Sydney, New South Wales, Australia.
Women's Health and Research Institute of Australia, Sydney, New South Wales, Australia.
出版信息
Aust N Z J Obstet Gynaecol. 2020 Aug;60(4):574-578. doi: 10.1111/ajo.13182. Epub 2020 May 26.
BACKGROUND
The diagnosis of Asherman syndrome, or 'intra-uterine adhesions' is often overlooked when the symptoms of amenorrhea and hematometra are missing.
AIMS
This audit reviews the clinical data of a large cohort of patients treated by a single operator.
MATERIALS AND METHODS
From July 1998 till the end of December 2017, 423 patients with intra-uterine adhesions were treated by a single operator. Clinical information was obtained by review of the medical files and phone interviews.
RESULTS
Amenorrhea was recorded in 163/423 patients (38.5%), 225/423 (53.2%) patients did not have amenorrhea and for 35/423 (8.3%) patients the information was missing. A hematometra was documented in 19/423 (4.5%) patients. Pregnancy was achieved in 215/246 (87.4%). Patients with stage II disease did best with a pregnancy rate of 94.5% (P = 0.029).
CONCLUSION
Asherman syndrome should be considered in any woman with a history of miscarriage or postpartum curettage who then fails to conceive again.
背景
当出现闭经和宫腔积血症状缺失时，Asherman 综合征（或“宫腔粘连”）的诊断往往被忽视。
目的
本研究对一位医生诊治的大样本宫腔粘连患者的临床资料进行了回顾性分析。
材料与方法
1998 年 7 月至 2017 年 12 月，一位医生对 423 例宫腔粘连患者进行了治疗。通过查阅病历和电话访谈获得了临床资料。
结果
闭经患者 163 例（38.5%），无闭经患者 225 例（53.2%），35 例患者（8.3%）的信息缺失。宫腔积血患者 19 例（4.5%）。246 例患者中有 215 例（87.4%）成功妊娠。Ⅱ期患者的妊娠率最高，为 94.5%（P=0.029）。
结论
对于有流产或产后刮宫史、随后未能再次怀孕的女性，应考虑 Asherman 综合征。
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