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硒对砷胁迫萝卜中抗氧化酶活性和砷生物可给性的影响。

Effects of selenium on antioxidant enzyme activity and bioaccessibility of arsenic in arsenic-stressed radish.

机构信息

Jiangxi Provincial Key Laboratory for Restoration of Degraded Ecosystems & Watershed Ecohydrology, Nanchang Institute of Technology, Nanchang, 330099, China.

Jiangxi Provincial Key Laboratory for Restoration of Degraded Ecosystems & Watershed Ecohydrology, Nanchang Institute of Technology, Nanchang, 330099, China.

出版信息

Ecotoxicol Environ Saf. 2020 Sep 1;200:110768. doi: 10.1016/j.ecoenv.2020.110768. Epub 2020 May 24.

Abstract

Consuming arsenic (As)-contaminated vegetables is the main route of As exposure in humans. The present study focused on the alterations in antioxidant enzymatic activities and As bioaccessibility in As-contaminated radish subjected to Se. Compared to the CK group, the total As content in raw radish was reduced by 27.5 ± 1.3%, and the bioaccessibility of As was reduced by 21.9 ± 2.3% in the 6 mg Se kg treatment group. The total As content in the treatment groups decreased first but then increased with increasing Se application in raw radish, gastric (G) fraction and gastrointestinal (GI) fraction, while the antioxidant activity exhibited the opposite trend. The results revealed that a low amount of Se effectively blocks the accumulation of As in radish, improves the antioxidant activity in radish and reduces the bioaccessibility of As. These findings provide new ideas for effectively alleviating the spread of As to the human body through the food chain.

摘要

食用砷(As)污染的蔬菜是人类暴露于 As 的主要途径。本研究重点关注了硒(Se)处理的受 As 污染的萝卜中抗氧化酶活性和 As 生物可利用性的变化。与 CK 组相比,生萝卜中的总 As 含量降低了 27.5±1.3%,6mg Se kg 处理组中 As 的生物可利用性降低了 21.9±2.3%。在生萝卜、胃(G)部分和胃肠道(GI)部分中,随着 Se 施用量的增加,总 As 含量先降低后升高,而抗氧化活性则呈现相反的趋势。结果表明,低剂量的 Se 可有效阻止 As 在萝卜中的积累,提高萝卜的抗氧化活性,降低 As 的生物可利用性。这些发现为通过食物链有效缓解 As 向人体扩散提供了新的思路。

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