School of Food Science, Washington State University, Pullman, Washington, USA.
Crit Rev Food Sci Nutr. 2021;61(11):1900-1913. doi: 10.1080/10408398.2020.1767537. Epub 2020 May 28.
Nutrition-related noncommunicable diseases (NR-NCDs) such as cardiovascular disease and type 2 diabetes both negatively impact the quality of life of many individuals and generate a substantial burden on society, demonstrating a need for intervention. Phytochemicals are investigated as a potential approach for combating NR-NCDs, and those found in hops have gained increased attention in recent decades. Hops, the strobile of the plant , are grown primarily for the brewing industry as they confer taste and increased shelf-life. The bitter acids represent the main compounds of interest for improving beer quality. Additionally, bitter acids as well as the prenylated chalcone xanthohumol, exhibit a wide range of health beneficial properties. This review summarizes those beneficial effects of bitter acids and xanthohumol on NR-NCDs, including inflammatory and immune diseases, obesity and metabolic disorders, as well as cancer prevention.
营养相关的非传染性疾病（NR-NCDs），如心血管疾病和 2 型糖尿病，都会降低许多人的生活质量，并给社会带来沉重负担，因此需要进行干预。植物化学物质被认为是对抗 NR-NCDs 的一种潜在方法，近年来，啤酒花中的植物化学物质受到了越来越多的关注。啤酒花是植物的花蕾，主要用于酿造行业，因为它们赋予了啤酒味道和更长的保质期。苦味酸是提高啤酒质量的主要关注化合物。此外，苦味酸和类姜黄素黄腐醇具有广泛的有益健康的特性。这篇综述总结了苦味酸和黄腐醇对 NR-NCDs 的有益作用，包括炎症和免疫性疾病、肥胖和代谢紊乱以及癌症预防。
