Larsen & Toubro Ocular Pathology Department, SankaraNethralaya , Chennai, India.
Ocul Immunol Inflamm. 2020 Nov 16;28(8):1187-1191. doi: 10.1080/09273948.2020.1754432. Epub 2020 May 28.
: To describe and quantify the benefit of ultra-widefield imaging in cases of Eales' disease during primary and follow-up visits. : This was a retrospective cross-sectional observational study screening case records of Eales' disease patients. Disease activity of each patient visit was assessed on clinical examination with indirect-ophthalmoscopy, ultra-widefield images (Optos) and widefield fluorescein angiography (FA) images. Clinical examination and Optos findings were compared with FA.The outcome measure was whether Optos and FA imaging helped in detecting disease activity better than clinical examination. : In total, 57 visits of 32 Eales'disease patients were analyzed. Disease activity was detected in 10/57 (17.5%) patient visits on clinical examination and in 20/57 (35%) patient visits on Optos. FA detected 29/57 (50.9%) patient visits as active vasculitis. Patient visits detected to have active vasculitis were significantly more with Optos and FA as compared to clinical examination ( = .017&0.0001, respectively). Widefield FA detected significantly more number of active vasculitis as compared to Optos ( = .043). : Ultra-widefield imaging is a very helpful tool in the management of a patient with Eales'disease.
描述和量化在初次就诊和随访期间，Eales 病患者接受超广角成像检查的获益，并对其进行量化评估。
这是一项回顾性的病例系列观察性研究，对 Eales 病患者的病例记录进行筛查。通过间接检眼镜、超广角图像（Optos）和宽视野荧光素血管造影（FA）图像对每位患者就诊时的疾病活动情况进行临床评估。将临床检查和 Optos 检查结果与 FA 进行比较。
Optos 和 FA 成像是否比临床检查更有助于检测疾病活动。
共分析了 32 例 Eales 病患者的 57 次就诊。在临床检查中发现 10/57（17.5%）例次的患者存在疾病活动，在 Optos 检查中发现 20/57（35%）例次的患者存在疾病活动。FA 检测到 29/57（50.9%）例次的患者存在活动性血管炎。与临床检查相比，Optos 和 FA 检查发现存在活动性血管炎的患者就诊次数明显更多（=0.017 和 0.0001）。宽视野 FA 检测到的活动性血管炎例次明显多于 Optos（=0.043）。
超广角成像在 Eales 病患者的管理中是一种非常有用的工具。
