Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, WHO, Geneva, Switzerland.
Int J Gynaecol Obstet. 2020 Sep;150(3):346-353. doi: 10.1002/ijgo.13241. Epub 2020 Jul 12.
To estimate the impact of the use of Intensive Care Units (ICU) in maternal mortality.
A secondary analysis of the WHO Multicountry Survey on Maternal and Newborn Health, a multicenter cross-sectional study conducted in maternity hospitals in 29 countries. Women who had severe maternal outcome (maternal death or maternal near-miss) and the availability and use of ICU beds were included. The women were categorized according to availability of ICU, and multivariate logistic regression analyses were performed to determine the risk of maternal death. To rate the severity of complications, the Maternal Severity Score (MSS) and the Maternal Severity Index (MSI) were used.
Of 314 623 women observed, 24 396 had severe complications. Of those, 16 981 (69.6%) were in facilities with ICUs; 1573 women were admitted to ICUs (6.4% of women with maternal complications and 0.5% of total). There is a significant protective effect for maternal mortality for patients with more severe conditions using ICUs (odds ratio 0.16, 95% confidence interval 0.07-0.33).
The use of ICU was associated with significantly reduced odds of maternal death in obstetric patients with severe clinical conditions. The availability and appropriate use of good-quality ICUs are therefore crucial to reduce maternal mortality.
评估重症监护病房(ICU)使用对产妇死亡率的影响。
这是一项针对世界卫生组织多国母婴健康调查的二次分析,该调查是一项多中心、横断面研究,在 29 个国家的产科医院进行。纳入患有严重产妇结局(产妇死亡或产妇接近死亡)且 ICU 床位可用并使用 ICU 床位的妇女。根据 ICU 的可用性对妇女进行分类,并进行多变量逻辑回归分析,以确定产妇死亡的风险。为了评估并发症的严重程度,使用了产妇严重程度评分(MSS)和产妇严重程度指数(MSI)。
在观察的 314623 名妇女中,有 24396 名患有严重并发症。其中,16981 名(69.6%)在设有 ICU 的设施中;1573 名妇女被收治在 ICU 中(占患有产妇并发症的妇女的 6.4%,占总人数的 0.5%)。患有更严重疾病并使用 ICU 的患者的产妇死亡率有显著的保护效应(比值比 0.16,95%置信区间 0.07-0.33)。
在患有严重临床疾病的产科患者中,使用 ICU 与产妇死亡率显著降低相关。因此,ICU 的可用性和适当使用高质量的 ICU 对于降低产妇死亡率至关重要。