Sarfraz Humaira, Chen Diana, Muhsen Ibrahim N, Schwartz Mary R, Ogbonna Martina
Internal Medicine, Houston Methodist Hospital, Houston, USA.
Pathology, Houston Methodist Hospital, Houston, USA.
Cureus. 2020 Apr 24;12(4):e7806. doi: 10.7759/cureus.7806.
Breast cancer is the most common malignancy affecting women. Metastatic involvement of the gastrointestinal (GI) tract secondary to a primary breast malignancy is rare. Here, we describe the case of a 60-year-old woman with a history of right lobular breast cancer (diagnosed and treated five years prior to presentation) who presented with fatigue, generalized abdominal pain, distension, weight loss, and vomiting. Her initial imaging was suspicious for a primary gynecological malignancy; however, subsequent workup showed a colonic mass. Total colonoscopy revealed colon metastases, and an immunohistochemical profile favored invasive lobular carcinoma of breast. Most cases of gastrointestinal metastases from breast cancer have lobular histology; however, colonic involvement is rare.
乳腺癌是影响女性的最常见恶性肿瘤。原发性乳腺恶性肿瘤继发胃肠道转移很少见。在此，我们描述了一例60岁女性，有右小叶乳腺癌病史（就诊前5年诊断并接受治疗），表现为疲劳、全腹痛、腹胀、体重减轻和呕吐。其初始影像学检查怀疑为原发性妇科恶性肿瘤；然而，后续检查发现结肠有肿物。全结肠镜检查显示结肠转移，免疫组化结果支持乳腺浸润性小叶癌。乳腺癌胃肠道转移的大多数病例为小叶组织学类型；然而，结肠受累很少见。
