Martins Figueiredo Luísa, Horta David Valadas, Reis Jorge A
Gastroenterology Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
GE Port J Gastroenterol. 2019 Oct;26(6):438-440. doi: 10.1159/000497043. Epub 2019 Mar 8.
Breast cancer is the most common tumour in women. Only 5-15% of breast cancer patients have distant metastases at diagnosis. Here we describe the case of a previously healthy 43-year-old woman with nausea, postprandial epigastric pain, and constipation as the first clinical presentation of breast cancer. Total colonoscopy revealed colon metastases and the immunohistochemical profile favoured primitive invasive lobular carcinoma of the breast. Gastrointestinal tract metastases are more frequent in lobular histology of breast cancer. Stomach and small intestine are the most common metastatic sites, while colon metastases are a rare occurrence.
乳腺癌是女性中最常见的肿瘤。仅5%-15%的乳腺癌患者在诊断时已有远处转移。在此，我们描述一例既往健康的43岁女性，其最初临床表现为恶心、餐后上腹部疼痛和便秘，最终被诊断为乳腺癌。全结肠镜检查发现结肠转移，免疫组化结果支持乳腺原发性浸润性小叶癌。胃肠道转移在乳腺癌小叶组织学类型中更为常见。胃和小肠是最常见的转移部位，而结肠转移则较为罕见。
