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应对激增:评估 COVID-19 对社区教学医院住院药房服务的早期影响。

Surviving the surge: Evaluation of early impact of COVID-19 on inpatient pharmacy services at a community teaching hospital.

机构信息

Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI.

Beaumont Hospital, Dearborn, Dearborn, MI.

出版信息

Am J Health Syst Pharm. 2020 Nov 16;77(23):1994-2002. doi: 10.1093/ajhp/zxaa189.

Abstract

PURPOSE

The coronavirus disease 2019 (COVID-19) pandemic has presented novel challenges to healthcare systems; however, an analysis of the impact of the pandemic on inpatient pharmacy services has not yet been conducted.

METHODS

Results of an observational assessment of operational and clinical pharmacy services at a community teaching hospital during the first weeks of the COVID-19 pandemic are presented. Service outcomes of the inpatient pharmacy were evaluated from February 1 to April 8, 2020. Outcomes during the weeks preceding the first COVID-19 admission (February 1 to March 11, 2020) and during the pandemic period (March 12 to April 8, 2020) were compared. Evaluated outcomes included daily order verifications, clinical interventions, and usage of relevant medications. An exploratory statistical analysis was conducted using Student's t test.

RESULTS

During the pandemic period, the number of new order verifications decreased from approximately 5,000 orders per day to 3,300 orders per day (P < 0.01), a reduction of 30% during the first 4 weeks of the pandemic compared to the weeks prior. Average daily pharmacokinetic dosing consults were reduced in the pandemic period (from 82 to 67; P < 0.01) compared to the prepandemic period; however, total daily pharmacist interventions did not differ significantly (473 vs 456; P = 0.68). Dispensing of hydroxychloroquine, azithromycin, enoxaparin, and sedative medications increased substantially during the pandemic period (P < 0.01 for all comparisons).

CONCLUSION

The operational and clinical requirements of an inpatient pharmacy department shifted considerably during the first weeks of the COVID-19 pandemic. Pharmacy departments must be adaptable in order to continue to provide effective pharmaceutical care during the pandemic.

摘要

目的

2019 年冠状病毒病(COVID-19)大流行给医疗系统带来了新的挑战;然而,目前尚未对大流行对住院药房服务的影响进行分析。

方法

介绍了 COVID-19 大流行初期一家社区教学医院运营和临床药学服务的观察性评估结果。评估了 2020 年 2 月 1 日至 4 月 8 日期间住院药房的服务结果。比较了大流行前第一例 COVID-19 入院前的两周(2020 年 2 月 1 日至 3 月 11 日)和大流行期间(2020 年 3 月 12 日至 4 月 8 日)的服务结果。评估的结果包括每天的医嘱核对、临床干预和相关药物的使用。使用学生 t 检验进行了探索性统计分析。

结果

在大流行期间,新医嘱核对的数量从每天约 5000 份减少到每天 3300 份(P<0.01),与大流行前的 4 周相比,大流行期间减少了 30%。大流行期间的每日药代动力学剂量咨询减少(从 82 次减少到 67 次;P<0.01)与大流行前相比;然而,每日药剂师干预总数没有显著差异(473 次对 456 次;P=0.68)。大流行期间羟氯喹、阿奇霉素、依诺肝素和镇静药物的配药量大幅增加(所有比较均 P<0.01)。

结论

COVID-19 大流行的第一周,住院药房部门的运营和临床需求发生了重大变化。药房部门必须具有适应性,以便在大流行期间继续提供有效的药学服务。

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