Zwirner J, Ondruschka B, Scholze M, Schulze-Tanzil G, Hammer N
Department of Anatomy, University of Otago, Dunedin, New Zealand.
Institute of Legal Medicine, University of Leipzig, Leipzig, Germany.
J Mech Behav Biomed Mater. 2020 Aug;108:103833. doi: 10.1016/j.jmbbm.2020.103833. Epub 2020 May 4.
The temporal muscle fascia (TMF) is a widely used graft material and of interest for computational simulations of the temporomandibular joint as well as computational and physical human head models in general. However, reliable biomechanical properties of the TMF are lacking to date. This study provides tensile data of 52 TMFs at an age range of 18 to 94 years. It further investigates, if acellular fascia scaffolds differ from native counterparts in their biomechanical behaviour. Native TMF has a median elastic modulus of 26.2 MPa (acellular: 24.5 MPa), an ultimate tensile strength of 2.9 MPa (acellular: 2.1 MPa), a maximum force of 12.6 N (acellular: 9.9 N) and a strain at failure of 14.1% (acellular: 14.8%). No significant difference was found regarding the properties of native and acellular samples. Elastic modulus and the ultimate tensile strength increased with age but only in the acellular group (p < 0.01). Decorin and fibronectin seemed to be washed out by the acellularization procedure. The absence of cells in acellular TMF samples is not of biomechanical relevance compared to the native state. Acellular TMF is a biomechanically promising scaffold material for graft purposes, which can be retrieved easily due to its superficial location.
颞肌筋膜（TMF）是一种广泛使用的移植材料，在颞下颌关节的计算模拟以及一般的人体头部计算模型和物理模型中都备受关注。然而，迄今为止，颞肌筋膜缺乏可靠的生物力学特性。本研究提供了52个年龄在18至94岁之间的颞肌筋膜的拉伸数据。它还进一步研究了脱细胞筋膜支架在生物力学行为上是否与天然的不同。天然颞肌筋膜的中位弹性模量为26.2兆帕（脱细胞：24.5兆帕），极限抗拉强度为2.9兆帕（脱细胞：2.1兆帕），最大力为12.6牛（脱细胞：9.9牛），断裂应变率为14.1%（脱细胞：14.8%）。在天然和脱细胞样本的特性方面未发现显著差异。弹性模量和极限抗拉强度随年龄增长，但仅在脱细胞组中如此（p < 0.01）。核心蛋白聚糖和纤连蛋白似乎在脱细胞过程中被洗脱。与天然状态相比，脱细胞颞肌筋膜样本中细胞的缺失在生物力学上并无关联。脱细胞颞肌筋膜是一种在生物力学上有前景的用于移植目的的支架材料，因其位置表浅，易于获取。
