Department of Anatomy, University of Otago, Dunedin, New Zealand.
Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sci Rep. 2021 Jan 22;11(1):2127. doi: 10.1038/s41598-020-80448-1.
The human temporal muscle fascia (TMF) is used frequently as a graft material for duraplasty. Encompassing biomechanical analyses of TMF are lacking, impeding a well-grounded biomechanical comparison of the TMF to other graft materials used for duraplasty, including the dura mater itself. In this study, we investigated the biomechanical properties of 74 human TMF samples in comparison to an age-matched group of dura mater samples. The TMF showed an elastic modulus of 36 ± 19 MPa, an ultimate tensile strength of 3.6 ± 1.7 MPa, a maximum force of 16 ± 8 N, a maximum strain of 13 ± 4% and a strain at failure of 17 ± 6%. Post-mortem interval correlated weakly with elastic modulus (r = 0.255, p = 0.048) and the strain at failure (r = - 0.306, p = 0.022) for TMF. The age of the donors did not reveal significant correlations to the TMF mechanical parameters. Compared to the dura mater, the here investigated TMF showed a significantly lower elastic modulus and ultimate tensile strength, but a larger strain at failure. The human TMF with a post-mortem interval of up to 146 h may be considered a mechanically suitable graft material for duraplasty when stored at a temperature of 4 °C.
人类颞肌筋膜（TMF）常被用作硬脑膜成形术的移植物材料。对 TMF 的生物力学分析还很缺乏，这阻碍了对 TMF 与其他用于硬脑膜成形术的移植物材料（包括硬脑膜本身）进行基于生物力学的充分比较。在这项研究中，我们研究了 74 个人类 TMF 样本与年龄匹配的硬脑膜样本的生物力学特性。TMF 的弹性模量为 36±19 MPa，极限拉伸强度为 3.6±1.7 MPa，最大力为 16±8 N，最大应变 13±4%，失效应变为 17±6%。尸检间隔与 TMF 的弹性模量（r=0.255，p=0.048）和失效应变（r=-0.306，p=0.022）呈弱相关。供体的年龄与 TMF 的力学参数没有显著相关性。与硬脑膜相比，这里研究的 TMF 表现出明显较低的弹性模量和极限拉伸强度，但失效应变较大。尸检间隔不超过 146 小时的人类 TMF 在 4°C 下储存时可能被认为是一种适合用于硬脑膜成形术的机械移植物材料。
