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Clinical differentiation of anticoagulant and non-anticoagulant properties of heparin.

作者信息

Thachil Jecko

机构信息

Department of Haematology, Manchester University Hospitals, Manchester, UK.

出版信息

J Thromb Haemost. 2020 Sep;18(9):2424-2425. doi: 10.1111/jth.14933. Epub 2020 Jun 25.

DOI:10.1111/jth.14933
PMID:32470198
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7283800/
Abstract
摘要

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本文引用的文献

1
Using heparin molecules to manage COVID-2019.使用肝素分子来应对2019冠状病毒病。
Res Pract Thromb Haemost. 2020 Jun 9;4(4):518-523. doi: 10.1002/rth2.12353. eCollection 2020 May.
2
Heparin - An old drug with multiple potential targets in Covid-19 therapy.肝素——一种在新冠病毒治疗中有多种潜在靶点的老药。
J Thromb Haemost. 2020 Sep;18(9):2422-2424. doi: 10.1111/jth.14898. Epub 2020 Aug 27.
3
Mild or Moderate Covid-19.轻度或中度新冠病毒感染
N Engl J Med. 2020 Oct 29;383(18):1757-1766. doi: 10.1056/NEJMcp2009249. Epub 2020 Apr 24.
4
More than an anticoagulant: Do heparins have direct anti-inflammatory effects?不仅仅是一种抗凝剂：肝素是否具有直接抗炎作用？
Thromb Haemost. 2017 Feb 28;117(3):437-444. doi: 10.1160/TH16-08-0620. Epub 2016 Dec 15.
5
Heparin-binding protein is important for vascular leak in sepsis.肝素结合蛋白对脓毒症时的血管渗漏很重要。
Intensive Care Med Exp. 2016 Dec;4(1):33. doi: 10.1186/s40635-016-0104-3. Epub 2016 Oct 4.
6
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis.肝素在脓毒症患者中的疗效与安全性：一项系统评价和荟萃分析。
Crit Care Med. 2015 Mar;43(3):511-8. doi: 10.1097/CCM.0000000000000763.
7
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.实验性脓毒症中肺内皮糖萼调节中性粒细胞黏附和肺损伤。
Nat Med. 2012 Aug;18(8):1217-23. doi: 10.1038/nm.2843. Epub 2012 Jul 22.
8
Inflammation induces hemorrhage in thrombocytopenia.炎症在血小板减少症中诱发出血。
Blood. 2008 May 15;111(10):4958-64. doi: 10.1182/blood-2007-11-123620. Epub 2008 Feb 6.