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射频心脏消融术中的主动食管冷却:数据更新,包括在超高功率短程消融中的应用

Proactive esophageal cooling during radiofrequency cardiac ablation: data update including applications in very high-power short duration ablation.

作者信息

Sharkoski Tiffany, Zagrodzky Jason, Warrier Nikhil, Doshi Rahul, Omotoye Samuel, Mercado Montoya Marcela, Gómez Bustamante Tatiana, Berjano Enrique, González Suárez Ana, Kulstad Erik, Metzl Mark

机构信息

Department of Clinical & Medical Affairs, Haemonetics, Boston, MA, USA.

Cardiac Electrophysiology, St. David's Medical Center, Texas Cardiac Arrhythmia Institute, Austin, TX, USA.

出版信息

Expert Rev Med Devices. 2025 Jan;22(1):63-73. doi: 10.1080/17434440.2024.2447809. Epub 2025 Jan 1.

Abstract

INTRODUCTION

Proactive esophageal cooling reduces injury during radiofrequency (RF) ablation of the left atrium (LA) for the treatment of atrial fibrillation (AF). New catheters are capable of higher wattage settings up to 90 W (very high-power short duration, vHPSD) for 4 s. Varying power and duration, however, does not eliminate the risk of thermal injury. Furthermore, alternative energy sources such as pulsed field ablation (PFA) also exhibit thermal effects, with clinical data showing esophageal temperatures up to 40.3°C. The ensoETM esophageal cooling device (Attune Medical, now a part of Haemonetics, Boston, MA, U.S.A.) is commercially available and FDA-cleared to reduce thermal injury to the esophagus during RF ablation for AF and is recommended in the 2024 expert consensus statement on catheter and surgical ablation of AF.

AREAS COVERED

This review summarizes growing evidence of esophageal cooling during high power RF ablation for AF treatment, including data relating to procedural efficacy, safety, and efficiency, and techniques to enhance operator success while providing directions for further research.

EXPERT OPINION

Proactive esophageal cooling reduces injury to the esophagus during high power RF ablation, and utilizing this approach may result in increased success in first-pass isolation, procedural efficiency, and long-term efficacy.

摘要

引言

在用于治疗心房颤动(AF)的左心房(LA)射频(RF)消融过程中,主动食管冷却可减少损伤。新型导管能够在高达90瓦的功率设置下(极高频短持续时间,vHPSD)持续4秒。然而,改变功率和持续时间并不能消除热损伤风险。此外,诸如脉冲场消融(PFA)等替代能源也会产生热效应,临床数据显示食管温度高达40.3°C。ensoETM食管冷却装置(Attune Medical,现为美国马萨诸塞州波士顿Haemonetics的一部分)已上市并获得美国食品药品监督管理局(FDA)批准,可在AF的RF消融过程中减少对食管的热损伤,并且在2024年AF导管和手术消融专家共识声明中被推荐使用。

涵盖领域

本综述总结了在高功率RF消融治疗AF过程中食管冷却的证据不断增加,包括与手术疗效、安全性和效率相关的数据,以及提高操作者成功率的技术,同时为进一步研究提供方向。

专家意见

主动食管冷却可减少高功率RF消融过程中对食管的损伤,采用这种方法可能会提高首次通过隔离的成功率、手术效率和长期疗效。

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Improved 1-year outcomes after active cooling during left atrial radiofrequency ablation.主动冷却可改善左心房射频消融术后 1 年的结果。
J Interv Card Electrophysiol. 2023 Oct;66(7):1621-1629. doi: 10.1007/s10840-023-01474-3. Epub 2023 Jan 21.

本文引用的文献

1
Considerations regarding safety with pulsed field ablation for atrial fibrillation.关于心房颤动脉冲场消融安全性的考量
Heart Rhythm O2. 2024 Aug 10;5(9):655-661. doi: 10.1016/j.hroo.2024.08.002. eCollection 2024 Sep.
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Clinical outcomes associated with an esophageal cooling device.与食管冷却装置相关的临床结果。
Heart Rhythm. 2024 Dec;21(12):2595-2597. doi: 10.1016/j.hrthm.2024.06.009. Epub 2024 Jun 13.

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