Cardiothoracic Department, University Hospital of Udine, Udine, Italy.
Infectious Diseases Clinic, Department of Medicine, University Hospital of Udine, Italy.
Cardiovasc Pathol. 2020 Sep-Oct;48:107223. doi: 10.1016/j.carpath.2020.107223. Epub 2020 Apr 28.
Saprochaete species infection is a rare fungal disease reported so far only in immunocompromised patients. We describe the first case of aortitis caused by Saprochaete capitata, presenting as ascending aorta aneurysm, with secondary endophthalmitis in an immunocompetent patient. Infection by Saprochaete capitata is potentially fatal, with a mortality ranging from 50% to 90% of cases. In the present case aortic aneurysm caused by Saprochaete capitata aortitis was successfully treated by the combination of accurate diagnosis with surgical and specific antifungal therapy.
棘壳菌属真菌感染是一种罕见的真菌感染病，目前仅在免疫功能低下的患者中报告过。我们描述了首例由卷枝毛壳菌引起的升主动脉炎，表现为升主动脉瘤，并伴有免疫功能正常患者的眼内炎。卷枝毛壳菌感染可能是致命的，病例的死亡率范围为 50%至 90%。在本病例中，由卷枝毛壳菌引起的主动脉瘤性升主动脉炎通过准确诊断与手术和特定抗真菌治疗相结合得到了成功治疗。
