Faculty of Applied Biological Sciences, Graduate School of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu City, Gifu 501-1193, Japan.
Department of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University, Kampus IPB Dramaga, Bogor 16680, West Java, Indonesia.
Molecules. 2020 May 27;25(11):2481. doi: 10.3390/molecules25112481.
Although the intake of jack bean ( (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1d, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-a-l-rhamnopyranosyl (1®6)- b-d-glucopyranosyl (1®2)-b-d-galactopyranosyl-7-O-[3-O--anisoyl]-a-l-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. This new compound was found to have a higher a-glucosidase inhibition activity compared to acarbose.
尽管食用刺桐（(L.) DC.）这种未充分利用的热带豆科植物可能有助于降低多种慢性疾病的风险，但目前针对其所含多酚类物质的研究还很少。因此，本研究旨在鉴定和定量分析刺桐中的主要多酚类物质，这些物质被认为具有抗氧化和其他生物活性。本研究共检测到并鉴定出四种主要化合物，均为三糖苷或四糖苷形式的山柰酚糖苷。通过紫外可见光谱、1D 和 2D NMR 以及高分辨电喷雾电离质谱（HR-ESI-MS）分析确定了它们的结构。具体而言，首次检测到山柰酚 3-O-a-l-鼠李吡喃糖苷基（1®6）-b-d-吡喃葡萄糖基（1®2）-b-d-吡喃半乳糖基-7-O-[3-O--阿魏酰]-a-l-鼠李吡喃糖苷，而其他三种化合物已在刺桐以外的植物中有所描述。与阿卡波糖相比，这种新化合物对α-葡萄糖苷酶的抑制活性更高。
