East London NHS Foundation Trust, 5-7 Rush Court, Bedford MK40 3JT, UK; University College London, London, UK; King's College London, London, UK.
East London NHS Foundation Trust, 5-7 Rush Court, Bedford MK40 3JT, UK.
Child Adolesc Psychiatr Clin N Am. 2020 Jul;29(3):483-500. doi: 10.1016/j.chc.2020.02.002. Epub 2020 Apr 3.
Epilepsy and autism frequently co-occur. Epilepsy confers an increased risk of autism and autism confers an increased risk of epilepsy. Specific epilepsy syndromes, intellectual disability, and female gender present a particular risk of autism in individuals with epilepsy. Epilepsy and autism are likely to share common etiologies, which predispose individuals to either or both conditions. Genetic factors, metabolic disorders, mitochondrial disorders, and immune dysfunction all can be implicated.
癫痫和自闭症经常同时发生。癫痫会增加自闭症的风险，自闭症会增加癫痫的风险。特定的癫痫综合征、智力障碍和女性性别在癫痫患者中存在特定的自闭症风险。癫痫和自闭症可能有共同的病因，使个体易患其中一种或两种疾病。遗传因素、代谢紊乱、线粒体疾病和免疫功能障碍都可能与此相关。
