Costa Anderson Alves, Wedy Glaucia Ferreira, Junior Walter Belda, Criado Paulo Ricardo
Department of Dermatology, Universidade de São Paulo, São Paulo, SP, Brazil.
Department of Dermatology, Universidade de São Paulo, São Paulo, SP, Brazil.
An Bras Dermatol. 2020 Jul-Aug;95(4):480-483. doi: 10.1016/j.abd.2019.10.005. Epub 2020 May 11.
Multinucleate cell angiohistiocytoma is a rare, benign vascular proliferation of unknown etiology. It occurs mainly in middle-aged women and usually affects the acral regions; the lesions appear as discrete, grouped, and asymptomatic violaceous papules. Histopathology shows proliferation and dilated small vessels in the papillary dermis, fibrous stroma with thickened collagen bundles, and multinucleated giant cells. To date, there are approximately 140 cases described in the indexed literature. This report presents the case of a 62-year-old woman with a typical clinical condition, who chose not undergo treatment, considering the benign character of her illness. The clinical and immunohistological aspects of this unusual dermatological entity are emphasized.
多核细胞血管组织细胞瘤是一种病因不明的罕见良性血管增生性疾病。主要发生于中年女性，通常累及手足部位；皮损表现为散在、成簇且无症状的紫蓝色丘疹。组织病理学显示乳头真皮层内小血管增生、扩张，纤维性间质中胶原束增厚，可见多核巨细胞。迄今为止，索引文献中报道的病例约有140例。本报告介绍了一名62岁患有典型临床症状的女性病例，鉴于其病情的良性特征，她选择不接受治疗。文中强调了这种罕见皮肤病实体的临床和免疫组织化学特征。
