University of Valencia Master's Degree in Public Health and Health Management, Camino del Cementerio,1, 46100, Burjassot, Valencia, Spain.
Neurophysiology Department, The American British Cowdray Medical Center, Sur 136 116, Las Americas, 01120, Mexico City, Mexico.
Toxicon. 2020 Sep;184:57-61. doi: 10.1016/j.toxicon.2020.05.018. Epub 2020 May 28.
The Amazonian Kambô frog, Phyllomedusa bicolor, is commonly known for the potential benefits of its secretion. The Kambô ritual consists in applying the toxin directly to a freshly burnt skin area, since it is believed by natives and shamans to purify and strengthen the body and mind of the user. We describe a 33-year old female with a history of periodic use of Kambô toxin who presented with a 3-week course of asthenia, malaise, myalgia, and proximal muscle weakness predominantly in the lower limbs. She had elevated muscle enzymes and an abnormal electromyography. We used the 2017 European League Against Rheumatism and American College of Rheumatology classification criteria to establish the diagnosis of dermatomyositis. The patient demonstrated clinical response to prednisone, with a complete recovery of signs and symptoms after 8 weeks of treatment. To our knowledge, this is the first case report of dermatomyositis possibly associated with the use of Kambô. The Kambô cleansing ritual is becoming popular in first world countries, but its use may lead to serious side-effects, sometimes life-threatening. In patients presenting with signs and symptoms suggestive of dermatomyositis and a skin line of circle-shaped burns, Phyllomedusa bicolor skin secretion exposure should be suspected.
亚马孙箭毒蛙，又称双色箭毒蛙，其分泌物具有潜在的益处，这一点广为人知。箭毒蛙仪式是指将毒素直接涂抹在刚刚烧伤的皮肤区域，因为当地人相信这种做法可以净化和增强使用者的身心。我们描述了一位 33 岁的女性，她有周期性使用箭毒蛙毒素的病史，出现了 3 周的乏力、不适、肌痛和四肢近端肌无力。她的肌肉酶升高，肌电图异常。我们使用 2017 年欧洲抗风湿病联盟和美国风湿病学会的分类标准来确立皮肌炎的诊断。该患者对泼尼松治疗有临床反应，经过 8 周的治疗后，所有症状和体征完全恢复。据我们所知，这是首例可能与使用箭毒蛙有关的皮肌炎病例报告。箭毒蛙清洁仪式在第一世界国家越来越流行，但它的使用可能会导致严重的副作用，有时甚至危及生命。对于出现皮肌炎体征和症状且皮肤有圆形烧伤线的患者，应怀疑接触过双色箭毒蛙的皮肤分泌物。
