Department of Orthodontics, Dental School, Isfahan University of Medical Sciences, Isfahan, Iran.
Dental Implants Research Center, Department of Prosthodontics, Dental School, Isfahan University of Medical Sciences, Isfahan, Iran.
J Evid Based Dent Pract. 2020 Jun;20(2):101405. doi: 10.1016/j.jebdp.2020.101405. Epub 2020 Jan 29.
White spot lesion (WSL) is recognized as the first clinical sign of enamel caries; it is a very critical phase because it can be prevented from progression to frank caries by changing the surrounding destructive environment. The present study was undertaken to systematically review the effect of resin infiltration (RI) technique on surface hardness (SH) of WSL.
Five electronic databases were searched with proper key words. Related titles and abstracts, up to October 2018, were screened, selected, and subjected to quality assessments. After collecting data, meta-analyses were carried out to compare the effect of RI with untreated WSL and sound enamel by using the STATA software.
A total of 4567 articles were included in the study after initial search. Finally, 10 studies were reliable enough in methodology to be included in the study. Metadata analyses, carried out on 7 studies that compared SH of RI group with untreated samples, showed a significant increase in SH with 3.66 mean difference (95% confidence interval = 2.56‒4.77, Q value = 36.07, I = 83.4%). However, meta-analysis on 4 studies that compared SH of RI with sound enamel showed a significant decrease in SH with -2.35 overall mean difference (95% confidence interval = -3.91-0.98, P = .00, Q value = 31.75, I = 90.6%).
The RI technique can enhance SH of WSL; however, regaining the SH of RI-treated WSLs similar to sound enamel is doubtful. Application of RI is more effective than other methods, including application of fluoride, enamel pro-varnish, adhesive, and colloidal silica infiltration for enhancing SH of WSLs.
白斑（WSL）被认为是牙釉质龋的第一个临床征象；这是一个非常关键的阶段，因为通过改变周围的破坏性环境，可以防止其进展为典型龋。本研究旨在系统回顾树脂渗透（RI）技术对 WSL 表面硬度（SH）的影响。
使用适当的关键词搜索了 5 个电子数据库。筛选、选择相关标题和摘要，并进行质量评估。收集数据后，使用 STATA 软件对 RI 组与未处理的 WSL 和正常釉质的效果进行荟萃分析。
初步搜索后，共纳入 4567 篇文章。最终，有 10 项研究在方法学上足够可靠，被纳入研究。对 7 项比较 RI 组与未处理样本 SH 的研究进行荟萃分析显示，SH 有显著增加，平均差异为 3.66（95%置信区间 2.56-4.77，Q 值 36.07，I 2 = 83.4%）。然而，对 4 项比较 RI 与正常釉质 SH 的研究进行荟萃分析显示，SH 有显著下降，总平均差异为-2.35（95%置信区间 -3.91-0.98，P =.00，Q 值 31.75，I 2 = 90.6%）。
RI 技术可以提高 WSL 的 SH；然而，恢复 RI 处理后的 WSL 的 SH 使其与正常釉质相似是值得怀疑的。与氟化物、釉质预涂剂、粘结剂和胶体二氧化硅渗透等其他方法相比，RI 的应用更有效，可以提高 WSL 的 SH。
