Department of Restorative, Preventive and Pediatric Dentistry, zmk bern, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
Department of Orthodontics and Dentofacial Orthopedics, zmk bern, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
Clin Oral Investig. 2021 Aug;25(8):4711-4719. doi: 10.1007/s00784-021-03931-7. Epub 2021 Jun 9.
The present review systematically analyzed clinical studies investigating the efficacy of resin infiltration on post-orthodontic or non-post-orthodontic, white spot lesions (WSL), or fluorosis.
Five electronic databases (Central, PubMed, Ovid MEDLINE, Ovid EMBASE, LILACS) were screened. Article selection and data abstraction were done in duplicate. No language or time restrictions were applied. Outcomes were visual-tactile or DIAGNOdent measurements.
Eleven studies with 1834 teeth being affected in 413 patients were included. Nine studies were randomized control trials, one a prospective cohort study, and one had an unclear study design. Meta-analysis could be performed for "resin infiltration vs. untreated control," "resin infiltration vs. fluoride varnish," and "resin infiltration without bleaching vs. resin infiltration with bleaching." WSL being treated with resin infiltration showed a significantly higher optical improvement than WSL without any treatment (standard mean difference (SMD) [95% CI] = 1.24 [0.59, 1.88], moderate level of evidence [visual-tactile assessment]) and with fluoride varnish application (mean difference (MD) [95% CI] = 4.76 [0.74, 8.78], moderate level of evidence [DIAGNOdent reading]). In patients with fluorosis, bleaching prior to resin infiltration showed no difference in the masking effect compared to infiltration alone (MD [95% CI] = - 0.30 [- 0.98, 0.39], moderate level of evidence).
Resin infiltration has a significantly higher masking effect than natural remineralization or regular application of fluoride varnishes. However, although the evidence was graded as moderate, this conclusion is based on only very few well-conducted RCTs.
Resin infiltration seems to be a viable option to esthetically mask enamel white spot lesions and fluorosis.
本综述系统分析了研究树脂渗透对正畸后或非正畸后、白色斑点（WSL）或氟斑牙疗效的临床研究。
筛选了 5 个电子数据库（CENTRAL、PubMed、Ovid MEDLINE、Ovid EMBASE、LILACS）。文章选择和数据提取均由两人完成。未设置语言或时间限制。结局指标为视觉触觉或 DIAGNOdent 测量值。
纳入了 11 项研究，涉及 413 名患者的 1834 颗牙齿。9 项研究为随机对照试验，1 项为前瞻性队列研究，1 项研究设计不明确。可对“树脂渗透与未治疗对照组”、“树脂渗透与氟化物漆”和“无漂白树脂渗透与漂白树脂渗透”进行荟萃分析。用树脂渗透治疗的 WSL 显示出明显更高的光学改善，优于未经任何治疗的 WSL（标准均数差（SMD）[95%CI]=1.24[0.59,1.88]，中等水平的证据[视觉触觉评估]）和用氟化物漆处理的 WSL（MD[95%CI]=4.76[0.74,8.78]，中等水平的证据[DIAGNOdent 读数]）。在氟斑牙患者中，与单独渗透相比，漂白前进行树脂渗透在掩蔽效果方面没有差异（MD[95%CI]=-0.30[-0.98,0.39]，中等水平的证据）。
树脂渗透的掩蔽效果明显高于自然再矿化或常规应用氟化物漆。然而，尽管证据被评为中等，但这一结论仅基于少数精心设计的 RCT。
树脂渗透似乎是一种可行的选择，可以掩饰釉质白色斑点和氟斑牙的美观。
