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非一般的关节:迈向银屑病关节炎的精准医学。

Not your average joint: Towards precision medicine in psoriatic arthritis.

机构信息

Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, United States of America.

Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, United States of America; Psoriatic Arthritis Center, New York University School of Medicine, New York, NY, United States of America.

出版信息

Clin Immunol. 2020 Aug;217:108470. doi: 10.1016/j.clim.2020.108470. Epub 2020 May 28.

Abstract

Precision medicine, propelled by advances in multi-omics methods and analytics, aims to revolutionize patient care by using clinically-actionable molecular markers to guide diagnostic and therapeutic decisions. We describe the applications of precision medicine in risk stratification, drug selection, and treatment response prediction in psoriatic arthritis, for which targeted, personalized approaches are steadily emerging.

摘要

精准医学通过多组学方法和分析技术的进步,旨在利用具有临床可操作性的分子标志物来指导诊断和治疗决策,从而彻底改变患者的护理方式。我们描述了精准医学在银屑病关节炎的风险分层、药物选择和治疗反应预测中的应用,针对这种疾病的靶向、个性化方法正在不断涌现。

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