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Medicine (Baltimore). 2020 Nov 25;99(48):e23357. doi: 10.1097/MD.0000000000023357.
2
Virtual screening of approved clinic drugs with main protease (3CL) reveals potential inhibitory effects on SARS-CoV-2.利用主要蛋白酶(3CL)对已批准临床药物进行虚拟筛选,揭示了其对 SARS-CoV-2 的潜在抑制作用。
J Biomol Struct Dyn. 2022 Feb;40(2):685-695. doi: 10.1080/07391102.2020.1817786. Epub 2020 Sep 10.
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Emerging coronaviruses: Genome structure, replication, and pathogenesis.新型冠状病毒:基因组结构、复制与发病机制
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Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells: A case report.人脐带间充质干细胞治疗危重症新型冠状病毒肺炎患者临床缓解一例报告
Medicine (Baltimore). 2020 Jul 31;99(31):e21429. doi: 10.1097/MD.0000000000021429.
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Temperature, Humidity, and Latitude Analysis to Estimate Potential Spread and Seasonality of Coronavirus Disease 2019 (COVID-19).温度、湿度和纬度分析估计 2019 年冠状病毒病(COVID-19)的潜在传播和季节性。
JAMA Netw Open. 2020 Jun 1;3(6):e2011834. doi: 10.1001/jamanetworkopen.2020.11834.
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Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study.在患有新冠肺炎、急性呼吸窘迫综合征和炎症反应过度的患者中使用高剂量阿那白滞素进行白细胞介素-1阻断:一项回顾性队列研究。
Lancet Rheumatol. 2020 Jun;2(6):e325-e331. doi: 10.1016/S2665-9913(20)30127-2. Epub 2020 May 7.
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Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and corticosteroids.针对 COVID-19 的治疗规划:使用多种免疫抑制剂的原理和假设:抗抗体、免疫球蛋白和皮质类固醇。
Int Immunopharmacol. 2020 Jul;84:106560. doi: 10.1016/j.intimp.2020.106560. Epub 2020 May 8.
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COVID-19: Developing from an Outbreak to A Pandemic.新型冠状病毒肺炎:从疫情爆发到全球大流行
Arch Med Res. 2020 Aug;51(6):582-584. doi: 10.1016/j.arcmed.2020.04.021. Epub 2020 May 13.
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新型冠状病毒肺炎:传播、预防和潜在治疗机会。

COVID-19: Transmission, prevention, and potential therapeutic opportunities.

机构信息

School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Zanjan, Iran.

Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein 2028, South Africa; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Boston, MA, USA.

出版信息

Clin Chim Acta. 2020 Sep;508:254-266. doi: 10.1016/j.cca.2020.05.044. Epub 2020 May 29.

DOI:10.1016/j.cca.2020.05.044
PMID:32474009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7256510/
Abstract

The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense research efforts worldwide, an effective vaccine and viable treatment options have eluded investigators. Therefore, infection prevention, early viral detection and identification of successful treatment protocols provide the best approach in controlling disease spread. In this review, current therapeutic options, preventive methods and transmission routes of COVID-19 are discussed.

摘要

新型冠状病毒病(COVID-19)疫情由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2)引起,仍然是一项全球性挑战。尽管全世界都在进行深入研究,但仍未能找到有效的疫苗和可行的治疗方法。因此,感染预防、早期病毒检测和确定成功的治疗方案是控制疾病传播的最佳方法。在这篇综述中,讨论了 COVID-19 的当前治疗选择、预防方法和传播途径。