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盲肠阿米巴病,类似炎症性肠病。

Cecal amebiasis mimicking inflammatory bowel disease.

机构信息

Department of Transportation & Logistics Management, National ChiaoTung University, Taipei, Taiwan.

Western Medicine Division, Lam Wah Ee Hospital, Penang, Malaysia.

出版信息

J Int Med Res. 2020 May;48(5):300060520922379. doi: 10.1177/0300060520922379.

DOI:10.1177/0300060520922379
PMID:32475192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7263159/
Abstract

Amebiasis is a frequently occurring parasitic infection in South East Asia. We present a case of a 54-year-old man with right lower quadrant abdominal pain that persisted for longer than 1 year. He had been diagnosed with inflammatory bowel disease in Indonesia. His abdominal pain persisted, despite therapy, and he visited Malaysia for transnational medical advice. Abdominal ultrasound showed fatty liver, gallbladder polyps, and a small left renal stone. Colonoscopy showed multiple ulcers in the cecum and a histopathological examination confirmed amebic infection of the cecum. The colonic ulcers subsided after anti-amebic treatment. This case highlights the need to consider the differential diagnosis of amebic colitis in patients presenting with manifestations of inflammatory bowel disease, especially in patients who live in or have traveled to endemic areas.

摘要

阿米巴病是东南亚地区常见的寄生虫感染。我们报告了 1 例 54 岁男性患者,其右下腹痛持续 1 年以上。他在印度尼西亚被诊断为炎症性肠病。尽管进行了治疗,他的腹痛仍持续存在,并前往马来西亚寻求跨国医疗建议。腹部超声显示脂肪肝、胆囊息肉和左肾结石。结肠镜检查显示盲肠有多个溃疡,组织病理学检查证实盲肠有阿米巴感染。抗阿米巴治疗后结肠溃疡消退。本病例强调了在表现为炎症性肠病的患者中需要考虑阿米巴结肠炎的鉴别诊断,特别是在居住在或曾前往流行地区的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8cb/7263159/6b4fd2d5e67f/10.1177_0300060520922379-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8cb/7263159/0430f4c20862/10.1177_0300060520922379-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8cb/7263159/6b4fd2d5e67f/10.1177_0300060520922379-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8cb/7263159/0430f4c20862/10.1177_0300060520922379-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8cb/7263159/6b4fd2d5e67f/10.1177_0300060520922379-fig2.jpg

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本文引用的文献

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A Review of the Global Burden, New Diagnostics, and Current Therapeutics for Amebiasis.阿米巴病的全球负担、新诊断方法及当前治疗手段综述
Open Forum Infect Dis. 2018 Jul 5;5(7):ofy161. doi: 10.1093/ofid/ofy161. eCollection 2018 Jul.
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Learning points from a case of severe amoebic colitis.一例严重阿米巴结肠炎的经验教训
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Fulminant Amebic Colitis after Corticosteroid Therapy: A Systematic Review.皮质类固醇治疗后暴发性阿米巴结肠炎:一项系统评价
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The differentiation of amebic colitis from inflammatory bowel disease on endoscopic mucosal biopsies.通过内镜下黏膜活检鉴别阿米巴结肠炎与炎症性肠病。
Indian J Pathol Microbiol. 2015 Oct-Dec;58(4):427-32. doi: 10.4103/0377-4929.168880.
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Colonoscopic diagnosis of amebiasis: a case series and systematic review.结肠镜检查对阿米巴病的诊断:病例系列及系统评价
Int J Colorectal Dis. 2015 Jan;30(1):31-41. doi: 10.1007/s00384-014-2040-6. Epub 2014 Oct 28.
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Caecal amoebic colitis mimicking a colorectal cancer.酷似结直肠癌的盲肠阿米巴结肠炎。
J Surg Case Rep. 2011 Nov 1;2011(11):1. doi: 10.1093/jscr/2011.11.1.
8
Novelties on amoebiasis: a neglected tropical disease.阿米巴病的新情况:一种被忽视的热带病。
J Glob Infect Dis. 2011 Apr;3(2):166-74. doi: 10.4103/0974-777X.81695.
9
Amebic colitis can mimic tuberculosis and inflammatory bowel disease on endoscopy and biopsy.阿米巴结肠炎在内镜检查和活检时可类似结核病和炎症性肠病。
Int J Surg Pathol. 2009 Apr;17(2):116-21. doi: 10.1177/1066896908316380. Epub 2008 May 21.
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Amebic colitis in asymptomatic subjects with positive fecal occult blood test results: clinical features different from symptomatic cases.粪便潜血试验结果呈阳性的无症状受试者的阿米巴结肠炎:临床特征与有症状病例不同。
Am J Trop Med Hyg. 2005 Nov;73(5):934-5.