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一例严重阿米巴结肠炎的经验教训

Learning points from a case of severe amoebic colitis.

作者信息

Petridou Christina, Al-Badri Adnan, Dua Anjana, Dryden Matthew, Saeed Kordo

机构信息

Microbiology Department, Hampshire Hospitals NHS Foundation Trust, Royal Hampshire County Hospital, Winchester, United Kingdom.

Pathology Department, Hampshire Hospitals NHS Foundation Trust, Royal Hampshire County Hospital, United Kingdom.

出版信息

Infez Med. 2017 Sep 1;25(3):281-284.

PMID:28956549
Abstract

A case of amoebic colitis and liver abscess is described in a previously fit 59-year old man who had been given the incorrect diagnosis of ulcerative colitis. His symptoms were so severe that a colectomy was being considered. The patient had a significant travel history including trips to Morocco, the Gambia and Cape Verde, putting him at risk of acquiring amoebic disease. However, this history was not ascertained until much later on in the disease process. The case highlighted crucial learning points including the importance of taking a lifelong travel history, the difficulties in telling ulcerative colitis and amoebic colitis apart both clinically and histopathologically, and the importance of sending multiple stool samples for parasitological microscopy analysis in patients being investigated for inflammatory bowel disease.

摘要

本文描述了一例阿米巴性结肠炎和肝脓肿病例,患者为一名59岁既往健康的男性,此前被误诊为溃疡性结肠炎。他的症状非常严重,以至于当时正在考虑进行结肠切除术。该患者有丰富的旅行史,包括前往摩洛哥、冈比亚和佛得角,这使他有感染阿米巴病的风险。然而,直到疾病进程的后期才查明这一病史。该病例突出了一些关键的经验教训,包括了解终生旅行史的重要性、在临床和组织病理学上区分溃疡性结肠炎和阿米巴性结肠炎的困难,以及在对炎症性肠病患者进行调查时,多次送检粪便样本进行寄生虫显微镜分析的重要性。

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1
Learning points from a case of severe amoebic colitis.一例严重阿米巴结肠炎的经验教训
Infez Med. 2017 Sep 1;25(3):281-284.
2
[Amebic colitis and amebic liver abscess--epidemiology and personal case report].[阿米巴性结肠炎与阿米巴肝脓肿——流行病学及个人病例报告]
Zentralbl Chir. 1997;122(3):197-200.
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Entamoeba histolytica infection in men who have sex with men.男性同性恋者中的溶组织内阿米巴感染。
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Amoebic liver abscess with negative serologic markers for Entamoeba histolytica: mind the gap!阿米巴肝脓肿伴阴性血清学标记物用于溶组织内阿米巴:注意差距!
Infection. 2012 Feb;40(1):87-91. doi: 10.1007/s15010-011-0157-x. Epub 2011 Jul 7.
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Intestinal amoebiasis and amoebic liver abscess in Brisbane, 1956 to 1973. Clinical syndromes and the results of medical and surgical management.1956年至1973年布里斯班的肠道阿米巴病和阿米巴肝脓肿。临床综合征以及内科和外科治疗结果。
Med J Aust. 1975 May 3;1(18):551-5.
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[Amebiasis].[阿米巴病]
Ugeskr Laeger. 2000 Mar 13;162(11):1537-41.
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Amebic colitis in an antigenically and serologically negative patient: usefulness of a small-subunit ribosomal RNA gene-based polymerase chain reaction in diagnosis.一名抗原和血清学检测均为阴性患者的阿米巴结肠炎:基于小亚基核糖体RNA基因的聚合酶链反应在诊断中的应用
Diagn Microbiol Infect Dis. 2008 Nov;62(3):333-5. doi: 10.1016/j.diagmicrobio.2008.06.014. Epub 2008 Aug 8.
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Amoebic liver abscess or is it?是阿米巴肝脓肿吗?还是另有其病?
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[Amoebic liver abscess in chronic colitis: revision of "Crohn disease" diagnosis].[慢性结肠炎中的阿米巴肝脓肿:“克罗恩病”诊断的修订]
Schweiz Med Wochenschr. 1999 Nov 6;129(44):1656-9.
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A case of amoebic colitis with amoeboma and simultaneous liver abscesses. A diagnosis by colonoscopy.一例伴有阿米巴瘤及同时存在肝脓肿的阿米巴结肠炎。经结肠镜检查确诊。
Acta Gastroenterol Belg. 2019 Oct-Dec;82(4):539-541.

引用本文的文献

1
Colitis caused by Entamoeba histolytica identified by real-time-PCR and fluorescence in situ hybridization from formalin-fixed, paraffin-embedded tissue.通过实时聚合酶链反应和荧光原位杂交技术,从福尔马林固定、石蜡包埋组织中鉴定出溶组织内阿米巴引起的结肠炎。
Eur J Microbiol Immunol (Bp). 2022 Sep 22;12(3):84-91. doi: 10.1556/1886.2022.00016.
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Cecal amebiasis mimicking inflammatory bowel disease.盲肠阿米巴病,类似炎症性肠病。
J Int Med Res. 2020 May;48(5):300060520922379. doi: 10.1177/0300060520922379.
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Nontravel-related invasive infection with probable heterosexual transmission.
非旅行相关的侵袭性感染,可能通过异性传播。
IDCases. 2019 Jul 9;18:e00592. doi: 10.1016/j.idcr.2019.e00592. eCollection 2019.
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Approach to amoebic colitis: Epidemiological, clinical and diagnostic considerations in a non-endemic context (Barcelona, 2007-2017).非流行地区阿米巴结肠炎的处理方法:流行病学、临床和诊断方面的考虑因素(巴塞罗那,2007-2017 年)。
PLoS One. 2019 Feb 21;14(2):e0212791. doi: 10.1371/journal.pone.0212791. eCollection 2019.