Royal Infirmary of Edinburgh; Honorary Senior Clinical Lecturer, University of Edinburgh, Edinburgh, UK.
Edinburgh Royal Infirmary, Edinburgh, UK.
Bone Joint J. 2020 Jun;102-B(6):716-726. doi: 10.1302/0301-620X.102B6.BJJ-2019-1434.R1.
This study aims to determine the proportion of patients with end-stage knee osteoarthritis (OA) possibly suitable for partial (PKA) or combined partial knee arthroplasty (CPKA) according to patterns of full-thickness cartilage loss and anterior cruciate ligament (ACL) status.
A cross-sectional analysis of 300 consecutive patients (mean age 69 years (SD 9.5, 44 to 91), mean body mass index (BMI) 30.6 (SD 5.5, 20 to 53), 178 female (59.3%)) undergoing total knee arthroplasty (TKA) for Kellgren-Lawrence grade ≥ 3 knee OA was conducted. The point of maximal tibial bone loss on preoperative lateral radiographs was determined as a percentage of the tibial diameter. At surgery, Lachman's test and ACL status were recorded. The presence of full-thickness cartilage loss within 16 articular surface regions (two patella, eight femoral, six tibial) was recorded.
According to articular cartilage loss and ACL status, 195/293 (67%) were suitable for PKA or CPKA: medial unicompartmental knee arthroplasty (UKA) 97/293 (33%); lateral UKA 25 (9%); medial bicompartmental arthroplasty 31 (11%); lateral bicompartmental arthroplasty 12 (4%); bicondylar-UKA 23 (8%); and patellofemoral arthroplasty (PFA) seven (2%). The ACL was intact in 166 (55%), frayed in 82 (27%), disrupted in 12 (4%), and absent in 33 (11%). Lachman testing was specific (97%) but poorly sensitive (38%) for disrupted/absent ACLs. The point of maximal tibial bone loss showed good interclass correlation (ICC 0.797, 0.73 to 0.85 95% confidence interval (CI); p < 0.001) and was more posterior when the ACL was absent. Maximum tibial bone loss occurring at > 55% of the anterior to posterior distance predicted ACL absence with 93% sensitivity and 91% specificity (area under the curve 0.97 (0.94 to 0.99 95% CI; p < 0.001).
ACL status can be reliably determined from a lateral radiograph using the location of maximal tibial bone loss. According to regions of cartilage loss and ACL status, two-thirds of patients with end-stage knee OA could potentially be treated with PKA or CPKA. Cite this article: 2020;102-B(6):716-726.
本研究旨在根据全层软骨损失和前交叉韧带(ACL)状况的模式,确定适合行部分(PKA)或联合部分膝关节置换术(CPKA)的终末期膝骨关节炎(OA)患者的比例。
对 300 例连续接受全膝关节置换术(TKA)治疗的患者(平均年龄 69 岁(SD 9.5,44 至 91),平均体重指数(BMI)30.6(SD 5.5,20 至 53),178 例女性(59.3%))进行了横断面分析。术前侧位 X 线片上胫骨骨丢失的最大点被确定为胫骨直径的百分比。术中记录lachman 试验和 ACL 状况。记录了 16 个关节表面区域(两个髌骨、8 个股骨、6 个胫骨)内全层软骨损失的存在情况。
根据关节软骨损失和 ACL 状况,293 例中有 195 例(67%)适合行 PKA 或 CPKA:内侧单间室膝关节置换术(UKA)97/293(33%);外侧 UKA25(9%);内侧双间室置换术 31 例(11%);外侧双间室置换术 12 例(4%);髁间 UKA23 例(8%);髌股关节置换术(PFA)7 例(2%)。ACL 完整 166 例(55%),ACL 磨损 82 例(27%),ACL 断裂 12 例(4%),ACL 缺失 33 例(11%)。Lachman 试验对 ACL 断裂/缺失具有很高的特异性(97%),但敏感性较差(38%)。胫骨最大骨丢失点的 ICC 为 0.797(0.73 至 0.85,95%置信区间(CI);p<0.001),当 ACL 缺失时,其位置更靠后。最大胫骨骨丢失发生在前后距离的>55%,预测 ACL 缺失的敏感性为 93%,特异性为 91%(曲线下面积 0.97(0.94 至 0.99,95%CI;p<0.001)。
可通过胫骨最大骨丢失的位置从侧位 X 线片上可靠地确定 ACL 状态。根据软骨损失和 ACL 状况的区域,三分之二的终末期膝骨关节炎患者可能需要行 PKA 或 CPKA 治疗。