Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Department of Neurological Surgery, University of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.
Neurosurg Clin N Am. 2020 Jul;31(3):301-308. doi: 10.1016/j.nec.2020.03.011.
We provide a history and overview of the network approach to epilepsy surgery. Models of the epileptogenic zone (EZ) have evolved considerably over the years with more recent models accounting for the connectivity and network properties of epileptic foci. Next, we describe several examples of network phenotypes of focal epilepsy and how these have the potential to influence surgical decision-making and patient outcome. Future research will provide new insight into how network models of the EZ can determine optimal surgical interventions that improve seizure outcomes and optimize cognitive outcomes.
我们提供了癫痫手术的网络方法的历史和概述。多年来，致痫区（EZ）的模型已经有了很大的发展，最近的模型考虑了癫痫灶的连通性和网络特性。接下来，我们描述了几种局灶性癫痫的网络表型，并探讨了它们如何有可能影响手术决策和患者预后。未来的研究将提供新的见解，了解 EZ 的网络模型如何确定最佳的手术干预措施，以改善癫痫发作的结果并优化认知结果。
