State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
Department of Pathology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
World J Gastroenterol. 2020 May 21;26(19):2286-2293. doi: 10.3748/wjg.v26.i19.2286.
In December 2019, a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China causing coronavirus disease-2019 (COVID-19). Numerous studies have shown varying degrees of liver damage in patients infected with SARS-CoV-2. However, in previous case studies of COVID-19, the exact cause of liver injury has not been clearly elucidated, nor is there clear evidence of the interaction between liver injury and COVID-19. This study will analyze the causes of liver injury in COVID-19 and the influence of liver-related complications on the treatment and prognosis of COVID-19.
2019 年 12 月,一种新型冠状病毒——严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)在中国武汉被发现,引发了 2019 年冠状病毒病(COVID-19)。大量研究表明,感染 SARS-CoV-2 的患者存在不同程度的肝损伤。然而,在之前 COVID-19 的病例研究中,肝损伤的确切原因尚未阐明,也没有明确的证据表明肝损伤与 COVID-19 之间存在相互作用。本研究将分析 COVID-19 中肝损伤的原因,以及肝相关并发症对 COVID-19 治疗和预后的影响。