Çoşğun Ibrahim Güven, Evyapan Fatma, Karabulut Nevzat
Afyonkarahisar State Hospital, Deparment of Chest Desease, Afyonkarahisar, Turkey.
Pamukkale University, Department of Chest Desease, Denizli, Turkey.
Sarcoidosis Vasc Diffuse Lung Dis. 2017;34(4):336-342. doi: 10.36141/svdld.v34i4.5791. Epub 2017 Apr 28.
Chest X-ray is correlated with pulmonary function of asbestos related disease. These correlations limited by low specific and sensitive. Computed tomography (CT) more sensitive. There was no adopted for the measurement of CT. Our aim in this study was to determine correlation between pleural plaque (PP) volume and lung function for use improving classification with CT. The study included 75 patients with environmental asbestos exposure. PP areas measured in patients were divided by the patient lung area to determine PP ratio with CT. Diffusing capacity and six minute walking distance (6MWD) measured and evaluated quality of life. Results:PP identified in 66 (88%) of the patients with CT. PP most frequently noted in the front right quadrant and had an average plaque volume of 7729,17 mm3. Plaque ratio taken as the percentage of the ratio to the lung volume, mean plaque percentage was 0,37±0,45% (0,003-2,3). In 12(18,1%) of the patients, asbestosis not seen with chest X-ray was detected with CT. PP volume and ratios were not statistically significantly correlated with respiratory functions, exercise capacity, cumulative amount of exposure. Patient of asbestos disease total lung capacity was lower, 6MWD distance was shorter and quality of life was poorer. .
胸部X线与石棉相关疾病的肺功能相关。这些相关性受限于低特异性和敏感性。计算机断层扫描(CT)更敏感。尚未采用CT测量方法。本研究的目的是确定胸膜斑(PP)体积与肺功能之间的相关性,以便利用CT改善分类。该研究纳入了75名有环境石棉暴露史的患者。通过将患者的PP面积除以患者的肺面积来确定CT下的PP比率。测量弥散能力和六分钟步行距离(6MWD)并评估生活质量。结果:66名(88%)患者通过CT发现有PP。PP最常出现在右前象限,平均斑块体积为7729.17立方毫米。斑块比率以占肺体积的百分比表示,平均斑块百分比为0.37±0.45%(0.003 - 2.3)。12名(18.1%)患者通过CT检测出胸部X线未发现的石棉肺。PP体积和比率与呼吸功能、运动能力、累积暴露量无统计学显著相关性。石棉病患者的肺总量较低,6MWD距离较短,生活质量较差。