评论：在tau蛋白病小鼠模型中，长期程序性死亡蛋白1（PD-1）检查点阻断不影响认知或促进tau蛋白清除。 - Suppr

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超能文献

Commentary: Chronic PD-1 Checkpoint Blockade Does Not Affect Cognition or Promote Tau Clearance in a Tauopathy Mouse Model.

作者信息

Baruch Kuti, Yoles Eti

机构信息

ImmunoBrain Checkpoint Ltd., Ness Ziona, Israel.

出版信息

Front Aging Neurosci. 2020 May 13;12:135. doi: 10.3389/fnagi.2020.00135. eCollection 2020.

DOI:10.3389/fnagi.2020.00135

PMID:32477102

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7237716/

Abstract

摘要

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Commentary: Chronic PD-1 Checkpoint Blockade Does Not Affect Cognition or Promote Tau Clearance in a Tauopathy Mouse Model.评论：在tau蛋白病小鼠模型中，长期程序性死亡蛋白1（PD-1）检查点阻断不影响认知或促进tau蛋白清除。

Front Aging Neurosci. 2020 May 13;12:135. doi: 10.3389/fnagi.2020.00135. eCollection 2020.

Response: Commentary: Chronic PD-1 Checkpoint Blockade Does Not Affect Cognition or Promote Tau Clearance in a Tauopathy Mouse Model.回应：评论：在tau蛋白病小鼠模型中，长期PD-1检查点阻断不影响认知或促进tau蛋白清除。

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Nat Commun. 2019 Jan 28;10(1):465. doi: 10.1038/s41467-019-08352-5.

Can immunotherapy treat neurodegeneration?免疫疗法能治疗神经退行性疾病吗？

Science. 2017 Jul 21;357(6348):254-255. doi: 10.1126/science.aai8231.

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.PD-1 免疫检查点阻断可减少阿尔茨海默病小鼠模型的病理并改善记忆。

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