Rout Arpita N, Sahu Kananbala, Sirka Chandra S
Department of Dermatology, AIIMS, Bhubaneswar, Odisha, India.
Indian Dermatol Online J. 2020 Mar 9;11(2):222-225. doi: 10.4103/idoj.IDOJ_153_19. eCollection 2020 Mar-Apr.
Pyoderma gangrenosum (PG) is a chronic neutrophilic dermatoses characterised by large ulcer healing with cribriform scar. PG can rarely occur over the healed scar. Its diagnosis depends on clinical morphology and exclusion of other diseases. We report a case of large pyoderma gangrenosum ulcer on a hypertrophic scar since 1 year. Biopsy from ulcer edge was suggestive of PG and hypertrophic scar. The hypertrophic scar had been formed by healing of a large ulcer 2 years back. The ulcer healed to two-third size over next three months with monthly dexamethasone pulse, daily oral steroid and dapsone. This case was unique since the PG ulcer had occurred over a hypertrophic scar. Such a presentation in PG is rare and physicians should be aware of such occurrence of PG.
坏疽性脓皮病（PG）是一种慢性嗜中性皮病，其特征为大溃疡愈合后形成筛状瘢痕。PG极少发生于愈合的瘢痕上。其诊断依赖于临床形态学及排除其他疾病。我们报告一例自1年前起发生于肥厚性瘢痕上的巨大坏疽性脓皮病溃疡病例。溃疡边缘活检提示为PG及肥厚性瘢痕。该肥厚性瘢痕是由2年前一个大溃疡愈合形成的。在接下来的三个月中，通过每月一次的地塞米松冲击治疗、每日口服类固醇及氨苯砜，溃疡愈合至原来大小的三分之二。该病例很独特，因为PG溃疡发生于肥厚性瘢痕上。PG的这种表现很罕见，医生应了解PG的这种情况。
