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自身免疫异常相关习惯性流产的治疗。两例报告。

Treatment of habitual abortions associated with autoimmune abnormalities. A report of two cases.

作者信息

Christiansen O B, Andersen E S, Lauritsen J G, Grunnet N

机构信息

Department of Clinical Immunology, Aalborg Hospital, Denmark.

出版信息

Acta Obstet Gynecol Scand. 1988;67(7):663-4. doi: 10.3109/00016348809004284.

DOI:10.3109/00016348809004284
PMID:3247841
Abstract

In a study of the etiology of idiopathic habitual abortion, we have found 2 patients with a history of 5 and 4 spontaneous abortions respectively, possibly caused by autoimmune abnormalities. In the plasma of one of the patients we had found the presence of lupus anticoagulans and other lupus antibodies, whereas the other suffered from a latent autoimmune hepatitis. We describe the successful treatment of the 2 womens' subsequent pregnancies with subcutaneous heparin supplemented with acetylsalicylic acid.

摘要

在一项关于特发性习惯性流产病因的研究中,我们发现了两名分别有过5次和4次自然流产史的患者,其流产可能是由自身免疫异常引起的。在其中一名患者的血浆中,我们发现了狼疮抗凝物和其他狼疮抗体,而另一名患者则患有潜在的自身免疫性肝炎。我们描述了用皮下注射肝素加乙酰水杨酸成功治疗这两名女性随后妊娠的情况。

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