Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA, USA.
J Feline Med Surg. 2021 Feb;23(2):74-78. doi: 10.1177/1098612X20926090. Epub 2020 Jun 1.
Urinary tract infections (UTIs) are reported to be relatively common in hyperthyroid cats, with prevalence rates ranging from 12% to 22%. Factors that are associated with UTIs include age, decreasing body weight and active urine sediments. The purpose of this study was to investigate the prevalence of positive urine cultures (PUCs) in hyperthyroid cats and associated risk factors for PUC.
In total, 197 hyperthyroid cats presenting for radioiodine therapy had urine cultures prospectively performed on cystocentesis samples. Data pertaining to clinical signs, drug history, age, weight, blood urea nitrogen, creatinine, serum thyroxine and urinalysis were also evaluated.
The prevalence of PUCs in this population of hyperthyroid cats was 5.1% and all cats were subclinical. Microscopic bacteriuria was significantly associated with a PUC (60%) compared with a negative urine culture (1.6%) status. Age, weight, urine specific gravity <1.020, urine pH, hematuria, pyuria, thyroxine concentration, breed and sex were not associated with PUC status.
The prevalence of PUCs in this population of cats was lower than previous reports of cats with hyperthyroidism. Cats with a PUC were subclinical at the time of culture, regardless of urine sediment abnormalities. Further studies are necessary to determine the clinical significance of subclinical bacteriuria in hyperthyroid cats.
据报道，甲状腺功能亢进的猫患尿路感染（UTI）较为常见，患病率为 12%至 22%。与 UTI 相关的因素包括年龄、体重下降和活跃的尿沉渣。本研究旨在调查甲状腺功能亢进的猫中阳性尿液培养（PUC）的流行率及其 PUC 的相关危险因素。
共对 197 只接受放射性碘治疗的甲状腺功能亢进的猫进行了经膀胱穿刺尿液培养的前瞻性研究。还评估了与临床症状、药物史、年龄、体重、血尿素氮、肌酐、血清甲状腺素和尿液分析有关的数据。
该组甲状腺功能亢进的猫中 PUC 的患病率为 5.1%，所有猫均为亚临床感染。与阴性尿液培养（1.6%）相比，显微镜下菌尿与 PUC 显著相关（60%）。年龄、体重、尿比重<1.020、尿 pH 值、血尿、脓尿、甲状腺素浓度、品种和性别与 PUC 状态无关。
该组猫的 PUC 患病率低于之前报道的甲状腺功能亢进猫的 PUC 患病率。在进行培养时，患有 PUC 的猫处于亚临床状态，无论尿液沉淀物是否异常。需要进一步研究来确定甲状腺功能亢进猫亚临床菌尿的临床意义。
