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猪和犊牛静脉注射双乙酰氧基雪腐镰刀菌烯醇后的组织残留

Tissue residues of diacetoxyscirpenol in pigs and calves after intravenous dosing.

作者信息

Coppock R W, Swanson S P, Gelberg H B, Buck W B

机构信息

Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois, Urbana 61801.

出版信息

Am J Vet Res. 1988 Nov;49(11):1997-9.

PMID:3247925
Abstract

Pigs (n = 19) were given 0, 0.1, 0.5, or 1 mg of diacetoxyscirpenol (DAS)/kg of body weight, and heifers (n = 7) were given 0 or 0.5 mg of DAS/kg. Animals were anesthetized and exsanguinated 8 hours after administration of DAS, and liver, kidney, skeletal muscle, mesenteric lymph node, and spleen were analyzed for DAS. Diacetoxyscirpenol was not detected in tissues from animals not given DAS. All tissues from pigs and calves given DAS contained at least traces (less than or equal to 10 ng/g of tissue) of DAS.

摘要

给19头猪分别注射0、0.1、0.5或1毫克/千克体重的二醋酸镳草镰刀菌烯醇(DAS),给7头小母牛分别注射0或0.5毫克/千克体重的DAS。给药8小时后对动物进行麻醉并处死放血,分析肝脏、肾脏、骨骼肌、肠系膜淋巴结和脾脏中的DAS。未注射DAS的动物组织中未检测到二醋酸镳草镰刀菌烯醇。注射了DAS的猪和小牛的所有组织中都至少含有微量(小于或等于10纳克/克组织)的DAS。

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