COVID-19 相关性脑炎酷似神经胶质肿瘤。
COVID-19-Associated Encephalitis Mimicking Glial Tumor.
机构信息
Department of Neurosurgery, Ondokuz Mayis University Samsun, Samsun, Turkey; Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Department of Neurosurgery, VM Medical Park Samsun Hospital, Samsun, Turkey.
出版信息
World Neurosurg. 2020 Aug;140:46-48. doi: 10.1016/j.wneu.2020.05.194. Epub 2020 May 29.
BACKGROUND
Reports on neurologic manifestations of coronavirus disease 2019 (COVID-19) have attracted broad attention. We present an unusual case of COVID-19-associated encephalitis mimicking a glial tumor.
CASE DESCRIPTION
A 35-year-old woman presented with headache and seizures. T2 fluid-attenuated inverse recovery imaging showed hyperintensities in the left temporal lobe. Magnetic resonance spectroscopy showed an elevated choline peak. Imaging findings were suggestive of high-grade glioma. Antiepileptic medication failed to achieve seizure control. A left anterior temporal lobectomy was performed. The patient had no postoperative deficits, and her symptoms completely improved. Histologic examination revealed encephalitis. Postoperatively, our patient tested positive for COVID-19.
CONCLUSIONS
Our case raises awareness of neurologic manifestations of the disease and their potential to mimic glial tumors. For prompt diagnosis and prevention of transmission, clinicians should consider COVID-19 in patients with similar presentation.
背景
关于 2019 年冠状病毒病（COVID-19）的神经表现的报告引起了广泛关注。我们报告了一例不常见的 COVID-19 相关性脑炎，其表现类似于神经胶质瘤。
病例描述
一名 35 岁女性因头痛和癫痫发作就诊。T2 液体衰减反转恢复成像显示左颞叶高信号。磁共振波谱显示胆碱峰升高。影像学表现提示高级别胶质瘤。抗癫痫药物未能控制癫痫发作。行左前颞叶切除术。患者术后无神经功能缺损，症状完全改善。组织学检查显示脑炎。术后，我们的患者 COVID-19 检测呈阳性。
结论
我们的病例提醒人们注意该疾病的神经表现及其模拟神经胶质瘤的可能性。为了及时诊断和防止传播，对于有类似表现的患者，临床医生应考虑 COVID-19。
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