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超重或肥胖及腹型肥胖与巴西学龄儿童心血管代谢危险因素的相关性:一项横断面研究。

Overweight or obesity and abdominal obesity and their association with cardiometabolic risk factors in Brazilian schoolchildren: A cross-sectional study.

机构信息

Federal University of Rio de Janeiro, Josue de Castro Nutrition Institute, Postgraduate Program in Nutrition, Rio de Janeiro, Brazil.

Federal University of Rio de Janeiro, Josué de Castro Nutrition Institute, Rio de Janeiro, Brazil.

出版信息

Nutrition. 2020 Oct;78:110780. doi: 10.1016/j.nut.2020.110780. Epub 2020 Mar 6.

Abstract

OBJECTIVES

The aim of this study was to access the association between overweight or obesity and abdominal obesity (AO) and cardiometabolic risk factors (CRF) of schoolchildren.

METHODS

We evaluated body weight (BW), height, body mass index (BMI), waist circumference (WC), fasting glycaemia (FG), blood pressure (BP), triacylglycerides (TGs), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in 501 students (6-10 y of age) from municipal schools in Macaé, Brazil. Statistical analyses were performed by χ, Fisher exact tests, and odds ratio (OR; 95% confidence interval [CI]).

RESULTS

Children with overweight or obesity had higher TG, TC, and BP values than normal weight children (P < 0.05). The same trend was observed in children with AO versus those without AO. Among the schoolchildren, 58.5% had at least one CRF. Overweight or obese children had increased risk for high BP (OR, 3.98; 95% CI, 2.4-6.57), high TGs (OR, 2.81; 95% CI, 1.64-4.8), high TC (OR, 2.47; 95% CI, 1.53-4), high LDL-C (OR, 3.07; 95% CI, 1.09-8.6) and two or more CRFs (OR, 4.6; 95% CI, 2.89-7.3). Children with AO had increased risk for high BP (OR, 3.97; 95% CI, 2.18-7.22), high TGs (OR, 3.4; 95% CI, 1.79-6.49), high TC (OR, 2.57; 95% CI, 1.39-4.75), high LDL-C (OR, 3.7; 95% CI, 1.24-11.07), and two or more CRFs (OR, 3.25; 95% CI, 1.82-5.78). Schoolchildren with CRFs presented higher means of BW, BMI, WC, FG, TGs, TC, LDL-C, SBP, DBP, and lower HDL-C than children without CRFs.

CONCLUSION

The relationship between increased body weight or AO and CRF, described in the present data, reinforces the importance of early prevention of excess weight in children.

摘要

目的

本研究旨在评估超重或肥胖与儿童腹型肥胖(AO)和心血管代谢风险因素(CRF)之间的关联。

方法

我们评估了 501 名(6-10 岁)来自巴西马卡埃市公立学校学生的体重(BW)、身高、体重指数(BMI)、腰围(WC)、空腹血糖(FG)、血压(BP)、三酰甘油(TGs)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)。采用 χ2、Fisher 确切检验和比值比(OR;95%置信区间[CI])进行统计分析。

结果

与体重正常的儿童相比,超重或肥胖的儿童 TG、TC 和 BP 值更高(P<0.05)。在有 AO 的儿童中也观察到了与无 AO 儿童相同的趋势。在这些学龄儿童中,有 58.5%至少存在一种 CRF。超重或肥胖的儿童发生高血压(OR,3.98;95%CI,2.4-6.57)、高 TGs(OR,2.81;95%CI,1.64-4.8)、高 TC(OR,2.47;95%CI,1.53-4)、高 LDL-C(OR,3.07;95%CI,1.09-8.6)和两种或更多 CRF(OR,4.6;95%CI,2.89-7.3)的风险增加。有 AO 的儿童发生高血压(OR,3.97;95%CI,2.18-7.22)、高 TGs(OR,3.4;95%CI,1.79-6.49)、高 TC(OR,2.57;95%CI,1.39-4.75)、高 LDL-C(OR,3.7;95%CI,1.24-11.07)和两种或更多 CRF(OR,3.25;95%CI,1.82-5.78)的风险增加。存在 CRF 的学龄儿童的 BW、BMI、WC、FG、TGs、TC、LDL-C、SBP、DBP 均值高于无 CRF 的儿童,而 HDL-C 均值则较低。

结论

本研究数据显示,体重增加或 AO 与 CRF 之间的关系,强调了儿童超重早期预防的重要性。

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