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Medicine (Baltimore). 2020 May 22;99(21):e20363. doi: 10.1097/MD.0000000000020363.
2
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本文引用的文献

1
Respiratory dysfunction in Parkinson's disease.帕金森病中的呼吸功能障碍。
J R Coll Physicians Edinb. 2017 Mar;47(1):35-39. doi: 10.4997/JRCPE.2017.108.
2
Asphyxia due to laryngeal spasm as a severe complication of awake deep brain stimulation for Parkinson's disease: a case report.喉痉挛导致的窒息作为帕金森病清醒状态下深部脑刺激的严重并发症:一例报告
BMC Neurol. 2016 Nov 8;16(1):216. doi: 10.1186/s12883-016-0736-7.
3
The clinical symptoms of Parkinson's disease.帕金森病的临床症状。
J Neurochem. 2016 Oct;139 Suppl 1:318-324. doi: 10.1111/jnc.13691. Epub 2016 Jul 11.
4
Parkinson's disease.帕金森病。
Lancet. 2015 Aug 29;386(9996):896-912. doi: 10.1016/S0140-6736(14)61393-3. Epub 2015 Apr 19.
5
Vocal cord paralysis and its etiologies: a prospective study.声带麻痹及其病因:一项前瞻性研究。
J Cardiovasc Thorac Res. 2014;6(1):47-50. doi: 10.5681/jcvtr.2014.009. Epub 2014 Mar 4.
6
Stridor in Parkinson's disease: a case of 'dry drowning'?帕金森病中的喘鸣:一例“干性溺水”?
J Laryngol Otol. 2010 Jun;124(6):668-73. doi: 10.1017/S0022215109992222. Epub 2009 Dec 11.
7
Laser arytenoidectomy for bilateral vocal fold palsy in Parkinson's disease.
J Laryngol Otol. 2005 Oct;119(10):831-3. doi: 10.1258/002221505774481345.
8
Parkinson's disease and anaesthesia.帕金森病与麻醉
Br J Anaesth. 2002 Dec;89(6):904-16. doi: 10.1093/bja/aef268.
9
Persistent perioperative laryngospasm in a patient with Parkinson's disease.一名帕金森病患者围手术期持续性喉痉挛
Can J Anaesth. 1998 May;45(5 Pt 1):495. doi: 10.1007/BF03012589.
10
Upper airway involvement in Parkinson's disease resulting in postoperative respiratory failure.帕金森病的上呼吸道受累导致术后呼吸衰竭。
Can J Anaesth. 1995 Apr;42(4):344-7. doi: 10.1007/BF03010713.

帕金森病患者全身麻醉拔管期间的上气道梗阻:一例报告

Upper airway obstruction during extubation after general anesthesia, in a patient with Parkinson disease: A case report.

作者信息

Sun Xiaodi, Dai Leyang, Pan Yinbing, Sha Huanhuan

机构信息

Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing Jiangsu, P.R. China.

出版信息

Medicine (Baltimore). 2020 May 22;99(21):e20363. doi: 10.1097/MD.0000000000020363.

DOI:10.1097/MD.0000000000020363
PMID:32481331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7249898/
Abstract

RATIONALE

Parkinson disease (PD) is a chronic neurodegenerative condition often suffered by the elderly. Upper airway obstruction, though rare in patients with PD, can be life threatening and is associated with vocal cord paralysis, laryngeal spasm, and dystonia of jaw and neck muscles.

PATIENT CONCERNS

We describe a life-threatening upper airway obstruction caused by bilateral vocal cord paralysis, in an elderly man with PD, during extubation after general anesthesia.

DIAGNOSES

Based on clinical presentation and visual laryngoscopy, the patient was diagnosed with laryngeal spasm and bilateral vocal cord paralysis after extubation.

INTERVENTIONS

Re-intubation was carried out and dopamine hydrazine tablets were administered via a nasal feeding tube.

OUTCOMES

After re-intubation and further treatment, the endotracheal tube was successfully removed and no symptoms of respiratory distress were observed.

LESSONS

Patients with PD may be at a risk of life-threatening upper airway obstruction after extubation, which should be prevented systematically.

摘要

理论依据

帕金森病(PD)是一种常见于老年人的慢性神经退行性疾病。上呼吸道梗阻在PD患者中虽罕见,但可能危及生命,且与声带麻痹、喉痉挛以及颌面部和颈部肌肉张力障碍有关。

患者情况

我们描述了一名患有PD的老年男性在全身麻醉拔管期间,因双侧声带麻痹导致危及生命的上呼吸道梗阻。

诊断

根据临床表现和喉镜检查,患者被诊断为拔管后喉痉挛和双侧声带麻痹。

干预措施

进行了再次插管,并通过鼻饲管给予多巴胺肼片。

结果

再次插管并进一步治疗后,气管导管成功拔除,未观察到呼吸窘迫症状。

经验教训

PD患者拔管后可能面临危及生命的上呼吸道梗阻风险,应进行系统预防。