新加坡五年研究期间 - 阳性阴沟肠杆菌复合体的基因组研究。
Genomic Study of -Positive Enterobacter cloacae Complex in Singapore over a Five-Year Study Period.
机构信息
National Public Health Laboratory, National Center for Infectious Diseases, Singapore.
National Centre for Infectious Diseases, Singapore.
出版信息
Antimicrob Agents Chemother. 2020 Jul 22;64(8). doi: 10.1128/AAC.00510-20.
Abstract
The gene is rarely detected outside the genus. Genomic characterization of 87 -positive complex members revealed that the largest phylogenomic clade was made up of subsp. (71.3%), followed by the newly described species (13.8%), (10.3%), and (4.6%). IMI-1 was the predominant carbapenemase variant (86/87, 98.9%). All the genes were associated with chromosomally integrated Xer-dependent integrative mobile elements (IMEXs), with two new variants detected.
摘要
该基因在属外很少被检测到。对 87 株阳性复合体成员的基因组特征分析表明，最大的系统发育分支由 亚种（71.3%）组成，其次是新描述的种 （13.8%）、 （10.3%）和 （4.6%）。IMI-1 是主要的碳青霉烯酶变异体（87/87，98.9%）。所有的 基因都与染色体整合的 Xer 依赖型整合移动元件（IMEXs）有关，检测到两种新的变体。
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