Walbolt Jarrett, Koh Yunsuk
Department of Health, Human Performance, and Recreation, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, USA.
J Obes Metab Syndr. 2020 Jun 30;29(2):114-123. doi: 10.7570/jomes19079.
Evidence linking the excessive consumption of nutritive sweeteners (NS) to adverse metabolic health outcomes has led to an increase in consumption of non-nutritive sweeteners (NNS), particularly among the obese and individuals with diabetes. NNS are characterized by having zero-to-negligible caloric load, while also having a sweet taste. They are utilized as a replacement for traditional NS to reduce energy intake and to limit carbohydrate-related negative health outcomes. However, recent studies have suggested that NNS may actually contribute to the development or worsening of metabolic diseases, including metabolic syndrome, obesity, type 2 diabetes, and cardiovascular disease. Thus, it is imperative to understand the NNS efficacy and the relationship between NNS and metabolic diseases.
将营养性甜味剂（NS）的过度摄入与不良代谢健康结果联系起来的证据，导致了非营养性甜味剂（NNS）的消费量增加，尤其是在肥胖者和糖尿病患者中。NNS的特点是热量负荷为零至可忽略不计，同时还具有甜味。它们被用作传统NS的替代品，以减少能量摄入并限制与碳水化合物相关的负面健康结果。然而，最近的研究表明，NNS实际上可能导致代谢疾病的发展或恶化，包括代谢综合征、肥胖症、2型糖尿病和心血管疾病。因此，了解NNS的功效以及NNS与代谢疾病之间的关系至关重要。
