Duncan A M, Buchwald M, Tsui L C
Department of Pathology, Queen's University, Kingston, Ontario, Canada.
Cytogenet Cell Genet. 1988;49(4):309-10. doi: 10.1159/000132684.
Two DNA sequences closely linked to the cystic fibrosis locus have been sublocalized to 7q31.3----q32 by in situ hybridization. These findings are consistent with previously published maps of that region of human chromosome 7. The cystic fibrosis locus therefore maps to the 7q31.3----q32 region, a more distal location that had been inferred from previous data.
通过原位杂交,已将与囊性纤维化基因座紧密连锁的两个DNA序列亚定位到7q31.3----q32。这些发现与先前发表的人类7号染色体该区域的图谱一致。因此,囊性纤维化基因座定位于7q31.3----q32区域,这是一个比先前数据推断的更靠远端的位置。