COVID-19 阳性肾胰联合移植受者的肾梗死。
Renal infarct in a COVID-19-positive kidney-pancreas transplant recipient.
机构信息
Department of Medicine, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
Division of Nephrology, Department of Medicine, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
出版信息
Am J Transplant. 2020 Nov;20(11):3221-3224. doi: 10.1111/ajt.16089. Epub 2020 Jun 24.
Abstract
The novel coronavirus disease 2019 (COVID-19) is associated with increased risk of thromboembolic events, but the extent and duration of this hypercoagulable state remain unknown. We describe the first case report of renal allograft infarction in a 46-year-old kidney-pancreas transplant recipient with no prior history of thromboembolism, who presented 26 days after diagnosis of COVID-19. At the time of renal infarct, he was COVID-19 symptom free and repeat test for SARS-CoV-2 was negative. This case report suggests that a hypercoagulable state may persist even after resolution of COVID-19. Further studies are required to determine thromboprophylaxis indications and duration in solid organ transplant recipients with COVID-19.
摘要
2019 年新型冠状病毒病（COVID-19）与血栓栓塞事件的风险增加相关，但这种高凝状态的程度和持续时间尚不清楚。我们描述了首例 COVID-19 诊断后 26 天发生的肾移植受者肾移植梗死的病例报告，该受者无血栓栓塞病史。在发生肾梗死时，他没有 COVID-19 症状，且 SARS-CoV-2 重复检测为阴性。本病例报告表明，高凝状态甚至在 COVID-19 痊愈后仍可能持续存在。需要进一步研究来确定 COVID-19 患者中实体器官移植受者的血栓预防指征和持续时间。
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