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狼疮患者感染新冠病毒后发生急性肾静脉血栓形成:一例病例报告及文献复习

Acute Renal Vein Thrombosis Following COVID-19 in a Lupus Patient: A Case Report and Review of the Literature.

作者信息

Petrou Dimitra, Sardeli Aggeliki, Vlachoyiannopoulos Panayiotis, Moschovaki-Zeiger Ornella, Lionaki Sophia

机构信息

Department of Nephrology, Attikon Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece.

Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.

出版信息

Life (Basel). 2023 May 25;13(6):1252. doi: 10.3390/life13061252.

Abstract

: The association between COVID-19 and hypercoagulability is well established. This is a case of a patient with systemic lupus erythematosus (SLE) who developed unilateral renal vein thrombosis following COVID-19, the third case described in the international literature so far. Clinical, laboratory characteristics and outcomes of the patient were described in detail. Literature review was performed on MEDLINE database via Pubmed. Search items included COVID-19, renal infarction, and renal thrombosis. A total of fifty-three cases were located. Of these, only two patients had renal vein thrombosis but none of them carried a diagnosis of SLE. However, six cases have been published so far involving SLE patients in whom thromboembolic events developed following COVID-19, but none of them experienced renal vein thrombosis. The present case adds a new piece to the emerging puzzle of COVID-19 associated hypercoagulability, especially among patients with autoimmune diseases.

摘要

新型冠状病毒肺炎(COVID-19)与高凝状态之间的关联已得到充分证实。这是一例系统性红斑狼疮(SLE)患者,在感染COVID-19后发生了单侧肾静脉血栓形成,这是迄今为止国际文献中描述的第三例。详细描述了该患者的临床、实验室特征及转归。通过PubMed在MEDLINE数据库上进行文献综述。检索词包括COVID-19、肾梗死和肾血栓形成。共找到53例。其中,仅有2例患者发生肾静脉血栓形成,但均未诊断为SLE。然而,迄今为止已发表6例涉及SLE患者在感染COVID-19后发生血栓栓塞事件的病例,但均未发生肾静脉血栓形成。本病例为COVID-19相关高凝状态这一新兴难题增添了新的内容,尤其是在自身免疫性疾病患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d77d/10305519/2fddf824c4bb/life-13-01252-g001.jpg

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