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慢性鼻窦炎治疗的多学科方法。

Multidisciplinary approach to the therapy of chronic sinusitis.

作者信息

Bassetti D, Concia E, Solbiati M, Sampietro M

机构信息

Faculty of Medicine and Surgery, University of Verona, Italy.

出版信息

Drugs Exp Clin Res. 1988;14(8):559-60.

PMID:3248509
Abstract

Twenty patients with maxillary sinusitis were treated with cefotetan (1 g, i.m.) twice a day. Samples of blood and maxillary sinus mucous membrane were taken in eight patients 2 h after dosing during the third day of therapy to evaluate drug concentration. Results show the excellent clinical and bacteriological effectiveness of cefotetan, as well as its high tissue penetration.

摘要

20例上颌窦炎患者接受头孢替坦治疗(1g,肌内注射,每日2次)。在治疗的第三天,8例患者在给药2小时后采集血液和上颌窦黏膜样本以评估药物浓度。结果显示头孢替坦具有出色的临床和细菌学疗效,以及较高的组织穿透力。

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