Bassetti D, Concia E, Solbiati M, Sampietro M
Faculty of Medicine and Surgery, University of Verona, Italy.
Drugs Exp Clin Res. 1988;14(8):559-60.
Twenty patients with maxillary sinusitis were treated with cefotetan (1 g, i.m.) twice a day. Samples of blood and maxillary sinus mucous membrane were taken in eight patients 2 h after dosing during the third day of therapy to evaluate drug concentration. Results show the excellent clinical and bacteriological effectiveness of cefotetan, as well as its high tissue penetration.
20例上颌窦炎患者接受头孢替坦治疗（1g，肌内注射，每日2次）。在治疗的第三天，8例患者在给药2小时后采集血液和上颌窦黏膜样本以评估药物浓度。结果显示头孢替坦具有出色的临床和细菌学疗效，以及较高的组织穿透力。
