激活卵子的可溶精子因子：PLCzeta 及其以外的因子。
The soluble sperm factor that activates the egg: PLCzeta and beyond.
机构信息
School of Biosciences, Cardiff University, Cardiff, UK.
出版信息
Reproduction. 2020 Jul;160(1):V9-V11. doi: 10.1530/REP-20-0079.
PMID:32485666
Abstract
PLCzeta(ζ) initiates Ca2+ oscillations and egg activation at fertilization in mammals, but studies in mouse eggs fertilized by PLCζ knockout (KO) sperm imply that there is another slow acting factor causing Ca2+ release. Here, I propose a hypothesis for how this second sperm factor might cause Ca2+ oscillations in mouse eggs.
摘要
PLCzeta(ζ) 在哺乳动物受精时引发 Ca2+ 振荡和卵子激活，但用 PLCzeta 敲除 (KO) 精子受精的小鼠卵子的研究表明，还有另一种缓慢作用的因子导致 Ca2+ 释放。在这里，我提出了一个假设，即这种第二种精子因子如何在小鼠卵子中引发 Ca2+ 振荡。
Zotero 插件