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虚拟现实减轻分娩女性的疼痛:一项随机对照试验。

Virtual Reality Reduces Pain in Laboring Women: A Randomized Controlled Trial.

作者信息

Wong Melissa S, Spiegel Brennan M R, Gregory Kimberly D

机构信息

Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California.

Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California.

出版信息

Am J Perinatol. 2021 Aug;38(S 01):e167-e172. doi: 10.1055/s-0040-1708851. Epub 2020 Jun 2.

Abstract

OBJECTIVE

Virtual reality (VR) represents a potential method for easing labor pain and in nonpregnant patients has been shown to achieve similar or greater analgesia than hydromorphone. Few studies of VR have been performed in pregnant women. The aim of this randomized controlled trial (RCT) is to evaluate whether VR is effective in reducing pain in laboring women.

STUDY DESIGN

An open-label, RCT of nulliparous, term women in labor in a tertiary care hospital. We included women with a pain score level of 4 to 7 having regular contractions at least every 5 minutes. We excluded women who had received any pharmacologic pain relief including neuraxial analgesia and those with contraindications to VR. Participants were randomized to up to 30 minutes of either VR or the control arm (no additional intervention). Our primary outcome was the difference in differences from pre- to postintervention pain score. Prespecified secondary outcomes included postintervention pain scores, duration of intervention use, pharmacologic analgesia use, maternal vitals, and obstetric outcomes.

RESULTS

From March 2018 to February 2019, 40 subjects were enrolled, randomized, and completed the study; 19 were randomized to control and 21 to the VR arm. Most baseline characteristics were similar between groups. For the primary outcome, those assigned to the control arm had a statistically significant increase in pain of +0.58, while the VR arm had a significant reduction in pain of -0.52 ( = 0.03). There was also a difference in the proportion who had a minimum clinically important difference in pain (0% control and 23.8% VR;  = 0.049). Postintervention maternal heart rate was higher in the control arm (86.8 vs. 76.3,  = 0.01). Most other secondary outcomes did not differ.

CONCLUSION

In our study, we found that VR was effective for reducing pain in women in labor as compared with those receiving no intervention.

KEY POINTS

· Virtual reality (VR) represents a nonpharmacologic option for pain relief.. · VR has been little studied in pregnant or laboring women.. · VR was associated with a reduction in pain in nulliparous women in labor..

摘要

目的

虚拟现实(VR)是一种缓解分娩疼痛的潜在方法,在非孕妇中已被证明能产生与氢吗啡酮相似或更强的镇痛效果。针对孕妇的VR研究很少。这项随机对照试验(RCT)的目的是评估VR是否能有效减轻分娩妇女的疼痛。

研究设计

一项针对三级护理医院中初产足月分娩妇女的开放标签RCT。我们纳入了疼痛评分在4至7级、至少每5分钟有规律宫缩的妇女。我们排除了接受过任何药物镇痛(包括椎管内镇痛)的妇女以及有VR禁忌症的妇女。参与者被随机分配到接受长达30分钟的VR或对照组(无额外干预)。我们的主要结局是干预前后疼痛评分的差异。预先设定的次要结局包括干预后的疼痛评分、干预使用时间、药物镇痛使用情况、产妇生命体征和产科结局。

结果

从2018年3月到2019年2月,40名受试者被纳入、随机分组并完成了研究;19人被随机分配到对照组,21人被分配到VR组。两组之间的大多数基线特征相似。对于主要结局,分配到对照组的妇女疼痛有统计学显著增加,增加了+0.58,而VR组疼痛显著降低,降低了-0.52(P = 0.03)。在疼痛方面有最小临床重要差异的比例也存在差异(对照组为0%,VR组为23.8%;P = 0.049)。干预后对照组的产妇心率较高(86.8对76.3,P = 0.01)。大多数其他次要结局没有差异。

结论

在我们的研究中,我们发现与未接受干预的妇女相比,VR对减轻分娩妇女的疼痛有效。

要点

· 虚拟现实(VR)是一种非药物镇痛选择。· 针对孕妇或分娩妇女的VR研究很少。· VR与初产分娩妇女的疼痛减轻有关。

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